Creative Biolabs

Alzheimer's 3Dish™ NeuCELL™ VM Human Neural Progenitor Cell Line, Clone D4

[CAT#: NCL-2108-P008]

Clonal FAD NeuCELL™ VM human neural progenitor cell line that expresses APPSL-GFP and PSEN1-mCherry.

Species:
Human
Applications:
Cell Culture
Cell Types:
Neural Stem Cell; Neural Progenitor Cell

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Description
Alzheimer's 3Dish™ FAD NeuCELL™® VM lines are a proprietary collection of immortalized single-cell derived clonal human neural progenitor cells that express stable levels of AD genes with multiple FAD mutations. The clonal FAD neural progenitor cells secrete different amounts of total Aþ and differ in the Aþ42/40 ratios. The clonal lines are notable in the homogeneity and relative stability of APP expression levels and pathogenic Aþ levels across multiple passages. The Alzheimer's 3Dish™ collection of clonal lines allows the direct assessment of the role of Aþ42/40 ratio in regulating phospho-tau accumulations and neurofibrillary tangles pathology in AD.
Cell Types
Neural Stem Cell; Neural Progenitor Cell
Applications
Cell Culture
Relevant Diseases
Alzheimer's Disease
Species
Human
Size
1 vial
Research Use Only
For research use only
Quality Control
Cells display normal karyotype as assessed by chromosome spread, STR profile and test negative for mycoplasma. Maternal blood has been screened for HIV, HTLV, Hepatitis B and C.
For Research Use Only. Not For Clinical Use.
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