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Creative Biolabs
Product

Alzheimer's 3Dish™ NeuCELL™ VM Human Neural Progenitor Cell Line, Clone D4

[CAT#: NCL-2108-P008]

Clonal FAD NeuCELL™ VM human neural progenitor cell line that expresses APPSL-GFP and PSEN1-mCherry.

Species:
Human
Applications:
Cell Culture
Cell Types:
Neural Stem Cell; Neural Progenitor Cell

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Product Overview

Description

A proprietary group of immortalised single-cell derived clonal human neural progenitor cells with numerous FAD mutations, Alzheimer's 3Dish™ FAD NeuCELL™® VM lines display steady amounts of AD genes. The A42/40 ratios and the overall A secretion rates of the clonal FAD neural progenitor cells vary. The homogeneity and relative stability of APP expression levels and pathogenic A levels through numerous passages in the clonal lines are noteworthy. The Alzheimer's 3Dish™ collection of clonal lines enables the direct evaluation of the A42/40 ratio's influence on the pathophysiology of neurofibrillary tangles and phospho-tau accumulations in AD.

Cell Types

Neural Stem Cell; Neural Progenitor Cell

Applications

Cell Culture

Relevant Diseases

Alzheimer's Disease

Species

Human
Properties

Size

>1x10^6 Cells

Research Use Only

For research use only

Quality Control

Cells display normal karyotype as assessed by chromosome spread, STR profile and test negative for mycoplasma. Maternal blood has been screened for HIV, HTLV, Hepatitis B and C.
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For Research Use Only. Not For Clinical Use.
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