Creative Biolabs

BIO [GSK-3 Inhibitors]

[CAT#: NMO1120FY326]

GSK-3 inhibitor

Target:
GSK-3

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Description
An effective, selective, reversible and ATP-competitive GSK-3α/β inhibitor (IC 50 = 5 nM). Without a feeder layer, BIO keeps embryonic stem cells (hESCs) in an undifferentiated state.
Synonyms
(2Z, 3E)-6'-Bromo-3-(hydroxyimino)-[2,3'-biindolinylidene]-2'-one
Molecular Weight
356.17
Form
Crystalline solid
Chemical Formula
C₁₆H₁₀BrN₃O₂
SMILES
C1=CC2=C(C(=C3C4=C(C=C(C=C4)Br)NC3=O)N=C2C=C1)NO
InChi
InChI=1S/C16H10BrN3O2/c17-8-5-6-9-12(7-8)19-16(21)13(9)15-14(20-22)10-3-1-2-4-11(10)18-15/h1-7,20,22H,(H,19,21)/b15-13-
InChi Key
WNWSUJQVZJJGLF-SQFISAMPSA-N
Solubility
DMSO (10 mg/ml) or EtOH (0.5 mg/ml)
IC50
IC₅₀ = 5 nM
CAS NO.
667463-62-9
PubChem Substance ID
5287844
MDL Number
MFCD08705318
Purity
≥98%
Storage
-20°C
Shipping
Gel Pack
Handling Advice
Protect from air and light
Research Use Only
For research use only
Target
GSK-3
Official Name
GSK-3
Full Name
Glycogen synthase kinase 3
Alternative Names
Glycogen Synthase Kinase 3; GSK3; Glycogen Synthase Kinase-3
Gene ID
2932(Human); 56637(Mouse); 84027(Rat)
Uniprot ID
P49841(Human); Q9WV60(Mouse); P18266(Rat)
For Research Use Only. Not For Clinical Use.
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