Creative Biolabs

C57BL/6J-Polr2k, Conditional Knockout Mouse (CRISPR/Cas9) [Frozen Sperm]

[CAT#: NAM-2102-ZP1190]

Target:
POLR2K
Strain:
C57BL/6J-Polr2k
Gene Modification Method:
Conditional knockout

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Description
Polr2k is located on chromosome 15 of mice. Using CRISPR/Cas9 technology, sgRNA and ssDNA are designed, and the Polr2k gene conditional knockout mice are obtained through high-throughput electrotransformation of fertilized eggs. After sexual maturity, sperms are taken and frozen.
Strain
C57BL/6J-Polr2k
Strain No.
CKOCMP-17749-Polr2k-B6J-VA
Stain Background
C57BL/6J
Gene Modification Method
Conditional knockout
MGI Phenotype
MGI:102725
Relevant Diseases
Huntington's Disease
Species
Mouse
Model Type
Frozen Sperm
Environment
SPF
Sperm Validation
Before sperm freezing: measure the concentration of mouse semen and observe sperm activity
Sperm freezing: 1 tube of frozen sperm is taken from each batch for in vitro fertilization, and more than 50% of fertilized eggs are obtained
Research Use Only
For research use only
Target
POLR2K
Alternative Names
ABC10-alpha;MafY;Mt1a;RPABC4;RPB10alpha;RPB12;RPB7.0
For Research Use Only. Not For Clinical Use.
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