Creative Biolabs

C57BL/6J-Prnp, Conditional Knockout Mouse (CRISPR/Cas9) [Frozen Sperm]

[CAT#: NAM-2102-ZP2042]

Target:
PRNP
Strain:
C57BL/6J-Prnp
Gene Modification Method:
Conditional knockout

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Product Overview

Description

Prnp is located on chromosome 2 of mice. Using CRISPR/Cas9 technology, sgRNA and ssDNA are designed, and the Prnp gene conditional knockout mice are obtained through high-throughput electrotransformation of fertilized eggs. After sexual maturity, sperms are taken and frozen.

Strain

C57BL/6J-Prnp

Strain No.

CKOCMP-19122-Prnp-B6J-VA

Stain Background

C57BL/6J

Gene Modification Method

Conditional knockout

MGI Phenotype

MGI:97769

Relevant Diseases

Prion Disease

Species

Mouse
Properties

Model Type

Frozen Sperm

Environment

SPF

Sperm Validation

Before sperm freezing: measure the concentration of mouse semen and observe sperm activity
Sperm freezing: 1 tube of frozen sperm is taken from each batch for in vitro fertilization, and more than 50% of fertilized eggs are obtained

Research Use Only

For research use only
Target Details

Target

PRNP

Alternative Names

AA960666;AI325101;CD230;PrP;PrP;PrPC;PrPSc;Prn-i;Prn-p;Sinc;prP27-30;prP33-35C
For Research Use Only. Not For Clinical Use.
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