Calcium Flux & cAMP Assay

Creative Biolabs is a renowned company at the forefront of neuroscience research and services. We are thrilled to introduce our Calcium Flux & cAMP Assay service, a cutting-edge solution for investigating intracellular signaling pathways.

Calcitonin Receptor Assay

Calcitonin receptors play a crucial role in calcium homeostasis and are involved in various physiological processes, including bone remodeling, calcium regulation, and neuronal function. Our Calcium Flux & cAMP Assay service includes a specific focus on the Calcitonin Receptor Assay, which allows for measuring both cAMP & Calcium concentration changes in the cytosol upon activation with calcitonin.

By using fluorescent Calcitonin Receptor Cell Line, we can monitor changes in intracellular calcium levels upon stimulation of the calcitonin receptor. These assays provide real-time, quantitative measurements of calcium flux, enabling the assessment of receptor functionality and pharmacological modulation.

High-throughput Calcium Flux Assays (FLIPR Assay)

At Creative Biolabs, we offer the FLIPR (Fluorometric Imaging Plate Reader) Assay, a cutting-edge technology that revolutionizes high-throughput screening in drug discovery and biomedical research. The FLIPR Assay enables rapid and accurate measurement of cellular responses, particularly changes in intracellular calcium levels, upon stimulation by various compounds or conditions. By measuring calcium flux in real-time, the FLIPR Assay provides valuable insights into the activity of cellular pathways and the effects of potential drugs or compounds. This approach allows for the screening of compound libraries, identification of lead candidates, and optimization of drug candidates for calcium-related targets.

The workflow of high-throughput Calcium Flux assays involves the following steps:

Applications of Calcium Flux & cAMP Assay

High-throughput Calcium Flux assays offer several advantages, including increased assay speed, reduced sample consumption, and the ability to screen large compound libraries. These assays are particularly useful in drug discovery and screening applications.

• Drug Discovery and Screening
• GPCR Pharmacology
• Ion Channel Function and Modulation
• Toxicity and Safety Assessment
• Neuronal Excitability and Synaptic Plasticity
• Neurotransmitter Research

Creative Biolabs' Calcium Flux & cAMP Assay service provides a powerful tool for investigating calcium flux and cAMP dynamics in diverse biological contexts. With applications ranging from GPCR signaling studies to neuronal excitability and endocrine disorders, our service facilitates breakthroughs in neuroscience research and therapeutic development.

Please feel free to contact us for more about our GPCR related services.