Acute Spinal Cord Injury Related Research Tools
Acute spinal cord injury (SCI) is a traumatic injury that either results in a bruise, a partial tear, or a complete tear in the spinal cord. It is a common cause of permanent disability and death in children and adults. The most common symptoms of acute spinal cord injuries may include:
- Muscle weakness
- Loss of voluntary muscle movement in the chest, arms, or legs
- Breathing problems
- Loss of feeling in the chest, arms, or legs
- Loss of bowel and bladder function
Efforts to prevent SCI include individual measures (e.g. safety equipment), societal measures (e.g. safety regulations in sports and traffic) and improvements of equipment. Improved emergency care, aggressive treatment and rehabilitation can minimize damage to the nervous system and even restore limited abilities. However, spinal cord injuries require long-term physical and occupational therapy if it interferes with activities of daily life.
Creative Biolabs aims to help our customers understand and diagnose acute spinal cord injury. We provide up-to-date products that are needed in SCI study. They include but are not limited to cell lines, monoclonal antibodies, polyclonal antibodies, labeled antibodies, proteins, analytical kits, and small molecules.
Pathways and Targets Related to Creative Biolabs SCI Products
| Pathways | Affiliating Targets |
| PEDF Induced Signaling | TNF, NOS2, NGFR, LEP, IL6, GRIN1 |
| Cytokine Signaling in the Immune System | TNF, NOS2, MMP9, IL6, GRIN1, GDNF |
| Toll-like Receptor Signaling Pathway | TNF, NOS2, MMP9, IL6, CXCL8, CASP3 |
| Pathways in Cancer | NOS2, MMP9, IL6, CXCL8, CASP3 |
| IL-17 Family Signaling Pathway | TNF, MMP9, IL6, CXCL8, CASP3 |
| Toll Comparative Pathway | TNF, NOS2, IL6, CXCL8 |
| Circadian Rythm Related Genes | NOS2, NGFR, LEP, IL6 |
| Pathogenic Escherichia coli Infection | TNF, IL6, CXCL8, CASP3 |
| Transcriptional Misregulation in Cancer | NGFR, MMP9, IL6, CXCL8 |
| Allograft Rejection | TNF, IL6, GDNF, CXCL8, CASP3 |
For Research Use Only. Not For Clinical Use.
Target
Related Products
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NeuroMab™ Mouse Anti-BDNF Monoclonal Antibody (CBP4590) [CAT#: NAB-2103-P070]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human; Bovine; Porcine; Canine
- Applications:
- WB; IP; IF
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2412
Product
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Antibodies
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- NeuroMab™ Anti-Tau Antibody(NRP-0422-P2293) (Cat#: NRP-0422-P2293)
Cells
- Green Fluorescent Alpha-synuclein SH-SY5Y Cell Line (Cat#: NCL2110P209)
- Mouse Microglia from C57BL/6 (Cat#: NCL-21P6-082)
- iNeu™ Human Neural Stem Cell Line (Cat#: NCL200552ZP)
- Mouse Midbrain Dopaminergic Neuron Cell MN9D (Cat#: NCL2110P059)
- Mouse Glioma Cell Line GL-261-Luc (Cat#: NCL-2108P06)
- Mouse Retinal Ganglion Cells (Cat#: NCL2110P145)
- Immortalized Human Cerebral Microvascular Endothelial Cells (Cat#: NCL-2108-P020)
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Kits
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
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- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
Tracers
- pAAV-hSyn-DIO-XCaMP-R-WPRE (Cat#: NTA-2012AD-P508)
- AAV2/9-hEF1a-fDIO-eNpHR 3.0-mCherry-WPRE-pA (Cat#: NTA-2012-ZP78)
- Dextran-CYanine5.5 (Cat#: NTA-2011-ZP118)
- pAAV-syn-FLEX-jGCaMP8f-WPRE (Cat#: NTA-2106-P064)
- rAAV-E-SARE-Cre-ERT2-PEST-WPRE-hGH polyA (Cat#: NTA-2010-TT342)
- rAAV-CAG-DIO-G-Flamp1 (Cat#: NRZP-0722-ZP719)
- pAAV-EF1a-DIO-EGFP-WPRE (Cat#: NTA-2012AD-P285)
- AAV2/9-hSyn-Flpo-EGFP-WPRE-pA (Cat#: NTA-2012-ZP149)
- pAAV-syn-FLEX-jGCaMP8s-WPRE (Cat#: NTA-2106-P066)
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Gene Related Products
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- Tau Antisense Oligonucleotide (IONIS-MAPTRx) (Cat#: NV-2106-P29)
Biospecimens
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
Cell Assay Reagents
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP502)
- NeuroPro™ Anti-EPO BBB Shuttle Protein (Cat#: NRZP-0423-ZP508)
- NeuroPro™ Anti-ASA BBB Shuttle Protein (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-IDS BBB Shuttle Protein (Cat#: NRZP-0423-ZP503)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP510)
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- NeuroPro™ Anti-NAGLU BBB Shuttle Protein (Cat#: NRZP-0423-ZP506)
