Brain Tumor Related Research Tools

A brain tumor occurs when abnormal cells propagate in the brain. There are two main types of brain tumors, non-cancerous (benign) and cancerous (malignant). Depending on the tumor’s size, type, and location, brain tumors have a variety of symptoms. The most common symptoms include headaches, seizures, memory loss, depression, vomiting and mental changes.

The cause of most brain tumors is unknown, but there are some risk factors related to brain tumor development such as age, radiation and genetic conditions. For example, mutations and deletions of tumor suppressor genes are thought to be the cause of some forms of brain tumors.

Recently, different methods are being studied for brain tumor treatments, such as dendritic cells or vaccines aimed at a specific molecule on the surface of the tumor cells. Creative Biolabs offers biological reagents needed in brain tumor studies including proteins, monoclonal antibodies against tumor biomarkers, tumor cell lines and animal models.

We’re here to help you better understand brain tumor types, diagnosis and treatments.

Biological Processes and Genes Related to Brain Tumor

Biological Processes	Genes
NOD-like receptor signaling pathway	IFNA1, DEFA3, DEFA1, ANTXR2
Defense response to gram-negative bacterium	DEFA3, DEFA1, CD4
Intracellular estrogen receptor signaling pathway	DEFA3, DEFA1
Mitochondrial fission	PRKN, MX1
Positive regulation of T cell proliferation	IL2RA, CD40LG, CD4
Membrane disruption in other organism	DEFA3, DEFA1
Defense response to virus	MX1, IFNA1, DEFA3, DEFA1
Defense response	MX1, IFNA1, DEFA3, DEFA1

For Research Use Only. Not For Clinical Use.

Target

Somatostatin 28

Hemojuvelin

Cables

LIS1

PGP9.5

DDR1

Alpha Synuclein

IFNGR1

Lgi1

Laminin alpha 5/LAMA5

AMIGO-1

CHRDL1

Synaptophysin

NF2

STXBP2

galectin 9/Gal-9

MAP3K4

WNT3A

VCAM1

FABP3

ECEL1

Munc13-1

DCAMKL1

GFAP

ACTA1

Nociceptin

S100 Beta

CDK2

ERK5

VRK1

Gemin 3

Niemann Pick C2