Brain Tumor Related Research Tools
A brain tumor occurs when abnormal cells propagate in the brain. There are two main types of brain tumors, non-cancerous (benign) and cancerous (malignant). Depending on the tumor’s size, type, and location, brain tumors have a variety of symptoms. The most common symptoms include headaches, seizures, memory loss, depression, vomiting and mental changes.
The cause of most brain tumors is unknown, but there are some risk factors related to brain tumor development such as age, radiation and genetic conditions. For example, mutations and deletions of tumor suppressor genes are thought to be the cause of some forms of brain tumors.
Recently, different methods are being studied for brain tumor treatments, such as dendritic cells or vaccines aimed at a specific molecule on the surface of the tumor cells. Creative Biolabs offers biological reagents needed in brain tumor studies including proteins, monoclonal antibodies against tumor biomarkers, tumor cell lines and animal models.
We’re here to help you better understand brain tumor types, diagnosis and treatments.
Biological Processes and Genes Related to Brain Tumor
| Biological Processes | Genes |
| NOD-like receptor signaling pathway | IFNA1, DEFA3, DEFA1, ANTXR2 |
| Defense response to gram-negative bacterium | DEFA3, DEFA1, CD4 |
| Intracellular estrogen receptor signaling pathway | DEFA3, DEFA1 |
| Mitochondrial fission | PRKN, MX1 |
| Positive regulation of T cell proliferation | IL2RA, CD40LG, CD4 |
| Membrane disruption in other organism | DEFA3, DEFA1 |
| Defense response to virus | MX1, IFNA1, DEFA3, DEFA1 |
| Defense response | MX1, IFNA1, DEFA3, DEFA1 |
For Research Use Only. Not For Clinical Use.
Target
Related Products
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NeuroMab™ Mouse Anti-LIS Monoclonal Antibody (CBP4811) [CAT#: NAB-2103-P439]
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP; IF; IHC-P; ELISA
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2592
Product
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Antibodies
- NeuroMab™ Anti-Integrin αvβ8 BBB Shuttle Antibody(NRZP-1222-ZP1218) (Cat#: NRZP-1222-ZP1218)
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- NeuroMab™ Rabbit Anti-Alpha-synuclein (CBP1631) (Cat#: NAB-08-PZ079)
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Cells
- iNeu™ Retinal Pigment Epithelial Cells (RPE) (Cat#: NRZP-0323-ZP92)
- Mouse Microglia Cell Line BV-2, Immortalized (Cat#: NCL2110P153)
- Immortalized Human Cerebral Microvascular Endothelial Cells (Cat#: NCL-2108-P020)
- Mouse Glioma Cell Line GL261-GFP (Cat#: NCL-2108P04)
- C57 Brain Cortex Neurons [Mouse] (Cat#: NCC20-9PZ48)
- Human Retinal Epithelial Cell ARPE-19 (Cat#: NCL2110P069)
- iNeu™ Human Neural Stem Cell Line (Cat#: NCL200552ZP)
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Kits
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
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- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
Tracers
- AAV2/9-hSyn-Flpo-EGFP-WPRE-pA (Cat#: NTA-2012-ZP149)
- pAAV-syn-FLEX-jGCaMP8s-WPRE (Cat#: NTA-2106-P066)
- Dextran-FITC (Cat#: NTA-2011-ZP110)
- Dextran, Cy5 Labeled, 2000 kDa (Cat#: NRZP-0722-ZP22)
- pAAV-EF1a-DIO-EGFP-WPRE (Cat#: NTA-2012AD-P285)
- PRV-CAG-EGFP (Cat#: NTA-2011-ZP14)
- pAAV-syn-jGCaMP8f-WPRE (Cat#: NTA-2106-P061)
- pAAV-syn-jGCaMP8m-WPRE (Cat#: NTA-2106-P062)
- VSV-eGFP (Cat#: NTA-2011-ZP20)
- AAV2 Full Capsids, Reference Standards (Cat#: NTC2101070CR)
Gene Related Products
- Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged (Cat#: NEP-0621-R0133)
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- ABCA1 Antisense Oligonucleotide (NV-2106-P27) (Cat#: NV-2106-P27)
Biospecimens
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
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Cell Assay Reagents
- NeuroPro™ Anti-ASA BBB Shuttle Protein (Cat#: NRZP-0423-ZP504)
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- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP500)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP498)
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