Brain Tumor Related Research Tools

A brain tumor occurs when abnormal cells propagate in the brain. There are two main types of brain tumors, non-cancerous (benign) and cancerous (malignant). Depending on the tumor’s size, type, and location, brain tumors have a variety of symptoms. The most common symptoms include headaches, seizures, memory loss, depression, vomiting and mental changes.

The cause of most brain tumors is unknown, but there are some risk factors related to brain tumor development such as age, radiation and genetic conditions. For example, mutations and deletions of tumor suppressor genes are thought to be the cause of some forms of brain tumors.

Recently, different methods are being studied for brain tumor treatments, such as dendritic cells or vaccines aimed at a specific molecule on the surface of the tumor cells. Creative Biolabs offers biological reagents needed in brain tumor studies including proteins, monoclonal antibodies against tumor biomarkers, tumor cell lines and animal models.

We’re here to help you better understand brain tumor types, diagnosis and treatments.

Biological Processes and Genes Related to Brain Tumor

Biological Processes	Genes
NOD-like receptor signaling pathway	IFNA1, DEFA3, DEFA1, ANTXR2
Defense response to gram-negative bacterium	DEFA3, DEFA1, CD4
Intracellular estrogen receptor signaling pathway	DEFA3, DEFA1
Mitochondrial fission	PRKN, MX1
Positive regulation of T cell proliferation	IL2RA, CD40LG, CD4
Membrane disruption in other organism	DEFA3, DEFA1
Defense response to virus	MX1, IFNA1, DEFA3, DEFA1
Defense response	MX1, IFNA1, DEFA3, DEFA1

For Research Use Only. Not For Clinical Use.

Target

Laminin alpha 5/LAMA5

VRK1

Apolipoprotein A1

Munc13-1

Hemojuvelin

Huntingtin

IFNGR1

Alpha Synuclein

Gemin 2

ZFP36

Insulin

p39

CHRDL1

Sarcoplasmic Reticulum

Cathepsin D

PTK6

HOMER1

DDR1

Mint-1

MAP3K4

LIS1

LRRK2

ERK5

Niemann Pick C2

ACTA1

FABP2

Cables

galectin 9/Gal-9

TORC2

AMIGO-1

STXBP2

VCAM1