Hydrocephalus Related Research Tools

Hydrocephalus (HC) is a condition where abnormal cerebrospinal fluid (CSF) is build up in the cavities of the brain. It is also called water in the brain. HC can be present at birth or developed in childhood or adulthood. It is divided into different categories, acquired hydrocephalus, congenital hydrocephalus, communicating hydrocephalus, non-communication hydrocephalus, normal pressure hydrocephalus and hydrocephalus ex-vacuo.

Now, little is understood about the causes of hydrocephalus. It is classically defined as a result of a dynamic imbalance between the production and absorption of CSF. The fluid accumulates in the two large lateral ventricles, resulting in an enlarged brain and skull. The accumulation of fluid eventually may cause neurological symptoms such as convulsions, intellectual disability, and epileptic seizures.

Creative Biolabs offers a wide range of tools, including specific antibodies as well as peptides and proteins targeting different biological processes of hydrocephalus. Our products are keenly sought by neuroscience researchers, particularly those applicable to studies involving hydrocephalus cause and various pathways.

Pathways Related to Hydrocephalus

Super pathways	Genes
PI3K-Akt signaling pathway	PTEN, PIK3R2, FGFR3, FGFR2, CCND2, AKT3
NFAT and cardiac hypertrophy	PTEN, PIK3R2, FGFR3, FGFR2, AKT3
Pathways in cancer	PTEN, PIK3R2, FGFR3, FGFR2, CCND2, AKT3
ErbB signaling pathway	PTEN, PIK3R2, FGFR3, FGFR2, AKT3
Apoptosis pathway	PIK3R2, FGFR3, FGFR2, AKT3

Molecular Functions Related to Hydrocephalus

Functions	Genes
Protein binding	ZIC3, WDR81, STK36, PTEN, PLOD1, PIK3R2
Protein kinase activity	STK36, FGFR3, FGFR2, CCND2, AKT3
Fibroblast growth factor-activated receptor activity	FGFR3, FGFR2

For Research Use Only. Not For Clinical Use.

Target

DLL3

PKC delta

PRKAR2A

LRRK2

PACSIN1

GBA

LNX

PHOX2A

PAK2

GFAP

SHANK1

IL-1α

SLC27A4

Netrin 1

CRMP2

Neurolysin

RGMA

Axin 2

NGF

PGP9.5

Synapsin I

CD45

OSP

Amyloid Beta

NKX2.2

Amisyn

Visfatin

GRIP1

Neurofilament H

EURL

Sarcoplasmic Reticulum

PAK1