- NeuroMab™ Anti-Amyloid Beta 1-15 Antibody,Clone NR2660P (Cat#: NRP-0422-P867)
- NeuroMab™ Anti-ApoC3 BBB Shuttle Antibody,Clone NR1616P (Cat#: NRZP-1022-ZP3505)
- NeuroMab™ Anti-pTau Antibody,Clone NR3595P (Cat#: NRP-0422-P1719)
- Tau Monoclonal Antibody (AT120, HT7 and BT2 clone) (Cat#: NK-2106-P008)
- NeuroMab™ Anti-CD20 Antibody,Clone NR3021P (Cat#: NRP-0422-P1230)
- NeuroMab™ Anti-CD32b Antibody, Clone NR130P (Cat#: NRP-0422-P1803)
- NeuroMab™ Anti-Tau Antibody,Clone NR2944P (Cat#: NRP-0422-P1684)
- NeuroMab™ Anti-EPHB2 Antibody,Clone NR1370P (Cat#: NRP-0422-P1220)
- NeuroMab™ Anti-F-Spondin/SPON1 Antibody, Clone N24875P (CBP11839) (Cat#: NRZP-0822-ZP4740)
- NeuroMab™ Anti-TREM2 Antibody, Clone NR65P (Cat#: NRP-0422-P792)
- Human Brain Vascular Pericytes (Cat#: NCL-21P6-015)
- Mouse Microglia Cell Line BV-2, Immortalized (Cat#: NCL2110P153)
- Rat Muller Cell (Cat#: NCL2110P040)
- Human CMEC/D3 Cell Line, Blood-Brain Barrier Model (Cat#: NCL-2108-P020)
- Sf295 Human Glioblastoma Cells (Cat#: NCL-2108P180)
- Human Microglia Cell Line HMC3, Immortalized (Cat#: NCL-2108P38)
- C57 Brain Cortex Neurons [Mouse] (Cat#: NCC20-9PZ48)
- Human Hippocampal Neuron Cells HPPNCs (Cat#: NCL2110P106)
- Mouse Glioma Cell Line GL-261-Luc (Cat#: NCL-2108P06)
- Mouse Microglia from C57BL/6 (Cat#: NCL-21P6-082)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Beta Amyloid (1-40), Aggregation Kit, TTF Assay (Cat#: NRZP-0323-ZP199)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- pAAV-syn-jGCaMP8s-WPRE (Cat#: NTA-2106-P063)
- pAAV-syn-jGCaMP8f-WPRE (Cat#: NTA-2106-P061)
- AAV2 Full Capsids, Reference Standards (Cat#: NTC2101070CR)
- AAV-mDLX-CRE-tdTomato (Cat#: NRZP-0622-ZP721)
- AAV2/9-hEF1a-DIO-mCherry-P2A-TetTox-WPRE-pA (Cat#: NTA-2012-ZP268)
- pAAV-syn-FLEX-jGCaMP8f-WPRE (Cat#: NTA-2106-P064)
- AAV-EF1a-mCherry-flex-dtA (Cat#: NRZP-0622-ZP616)
- Dextran-FITC (Cat#: NTA-2011-ZP110)
- AAV2/9-hSyn-Flpo-EGFP-WPRE-pA (Cat#: NTA-2012-ZP149)
- pAAV-syn-FLEX-jGCaMP8m-WPRE (Cat#: NTA-2106-P065)
- Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged (Cat#: NEP-0421-R0140)
- Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged (Cat#: NEP-0621-R0133)
- Lenti of Mouse synuclein, alpha (Snca) transcript variant (NM_001042451) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0864)
- Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0676)
- Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged (Cat#: NEP-0421-R0232)
- ABCA1 Antisense Oligonucleotide (AK311445) (Cat#: NV-2106-P27)
- Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0832)
- Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged (Cat#: NEP-0521-R0808)
- Mouse SOD1 shRNA Silencing Adenovirus (Cat#: NV-2106-P14)
- Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged (Cat#: NEP-0621-R0041)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroPro™ Anti-Erythropoietin BBB Shuttle Protein, cTfRMAb-EPO (Cat#: NRZP-0423-ZP499)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein, HIRMab-IDUA (Cat#: NRZP-0423-ZP502)
- NeuroPro™ Anti-EPO BBB Shuttle Protein, HIRMab-EPO (Cat#: NRZP-0423-ZP508)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein, cTfRMAb-GDNF (Cat#: NRZP-0423-ZP500)
- NeuroPro™ Anti-IDS BBB Shuttle Protein, HIRMab-IDS (Cat#: NRZP-0423-ZP503)
- NeuroPro™ Anti-PON1 BBB Shuttle Protein, HIRMab-PON1 (Cat#: NRZP-0423-ZP507)
- NeuroPro™ Anti-idursulfase BBB Shuttle Protein, 8D3-IL-1RA (Cat#: NRZP-0423-ZP497)
- NeuroPro™ Anti-SGSH BBB Shuttle Protein, HIRMab-SGSH (Cat#: NRZP-0423-ZP505)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein, HIRMab-GDNF (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-NAGLU BBB Shuttle Protein, HIRMab-NAGLU (Cat#: NRZP-0423-ZP506)
Labeled Dextran Conjugate Products
Dextran is a natural synthetic polysaccharide with good water solubility, low toxicity and different molecular weight. They have been successfully used as long-term tracers for living cells. Our dextran is purified by size chromatography to remove unbound molecules and ensure proper cell biology analysis applications. Dextran is functionalized with various groups, dyes and other biomolecules.
Dextrans Features
Dextrans is a hydrophilic polysaccharide synthesized by Leuconostoc bacteria. They have a high molecular weight and have various sizes after fractionation. Dextran has good water solubility, low toxicity and relatively inertness. Their α-1,6-polyglucose bonds are resistant to cleavage by most endogenous cellular glycosidases. These properties enable Dextrans to be used as an effective water-soluble carrier for dyes, indicators and reactive groups in various applications, especially as a long-term tracer for living cells. Dextran conjugates with a variety of molecular weights (3 000, 10 000, 40 000, 70 000, 500 000) and labeled with a wide range of substituents can be used.
Advantages of Dextran for neuron staining:
- 3,000 and 10,000 MW
- Direct fluorescence or secondary detection
- Loading by microinjection or iontophoresis
- Repairable and light stabilized options
Applications
Fluorescent and biotinylated dextran are commonly used to track neuronal projections. Dextran conjugates with a molecular weight of up to 70 000 Daltons are widely used to track neuronal projections. The 3 000 MW dextran conjugate penetrates the peripheral neuronal processes better than the high MW dextran and diffuses faster. In contrast, 10,000 MW dextran remains in the cell and does not cross gap junctions. They distribute slowly, but the cells retain longer. The 10,000 MW AlexaFluor® conjugate is generally brighter and more light resistant. Most conjugates are lysine immobilized and can be used in combination with antibody labels. The labeled dextran can be effectively used as an antegrade or retrograde tracer, depending on the research method and tissue type used.
3,000 MW Dextran | 3,000 MW Dextran, Fluorophore, Biotin | 10,000 MW Dextran, Alexa Fluor® | 10,000 MW Dextran, Fluorophore, Biotin | |
Readout | Direct fluorescence imaging of cells | Direct fluorescence imaging of cells; biotins easily accept secondary detection to amplify weak signals | Direct fluorescence imaging of cells | Direct fluorescence imaging of cells; biotins easily accept secondary detection to amplify weak signals |
Carrier | Dextran, 3,000 MW | Dextran, biotin, 3,000 MW | Dextran, 10,000 MW | Dextran, biotin 10,000 MW |
Tissue sections | Yes | Yes | ||
In vivo neurons | Yes | Yes | ||
Fixed tissue sections | No | No | ||
Cultured cells | Yes | Yes | ||
Cell loading | Microinjection | Microinjection | ||
Staining mode | Endogenous | Endogenous | ||
Best for | Single cells | Single cells | ||
Fixable | Lysine-fixable | |||
Transport | Bidirectional | Bidirectional | ||
Synaptic transfer | No | No | ||
Gap junction transfer | Yes | No |
Cat. No. | Product Name | Standard filter set(s) | Fluorophore | Ex/Em (nm) |
NTA-2011-ZP90 | Dextran, Biotin-Conjugated, 3,000 MW [Lysine-Fixable] [Lysine-Fixable] | NA | Biotin | NA |
NTA-2011-ZP91 | Dextran, Fluorescein and Biotin-Conjugated, 3,000 MW [Lysine-Fixable] | FITC | Fluorescein | 494/518 |
NTA-2011-ZP92 | Dextran, Tetramethylrhodamine and Biotin-Conjugated, 3,000 MW [Lysine-Fixable] | TAMRA | TAMRA | 555/580 |
NTA-2011-ZP93 | Dextran, Fluorescein-Conjugated, 3,000 MW [Lysine-Fixable] | FITC | Fluorescein | 494/521 |
NTA-2011-ZP94 | Dextran, Tetramethylrhodamine-Conjugated, 3,000 MW [Lysine-Fixable] | TAMRA | TAMRA | 555/580 |
NTA-2011-ZP95 | Dextran, Texas Red®-Conjugated, 3,000 MW [Lysine-Fixable] | Texas Red® | Texas Red® | 595/615 |
NTA-2011-ZP96 | Dextran, Rhodamine Green-Conjugated, 3,000 MW [Non-Fixable] | FITC | Rhodamine Green | 502/527 |
NTA-2011-ZP97 | Dextran, Tetramethylrhodamine-Conjugated, 3,000 MW [Non-Fixable] | TAMRA | TAMRA | 555/580 |
NTA-2011-ZP98 | Dextran, Texas Red®-Conjugated, 3,000 MW [Non-Fixable] | Texas Red® | Texas Red® | 595/615 |
Cat. No. | Product Name | Standard filter set(s) | Fluorophore | Ex/Em (nm) |
NTA-2011-ZP99 | Dextran, Alexa Fluor® 488-Conjugated, 10,000 MW | FITC | Alexa Fluor® 488 | 495/519 |
NTA-2011-ZP100 | Dextran, Alexa Fluor® 546-Conjugated, 10,000 MW | TRITC | Alexa Fluor® 546 | 556/573 |
NTA-2011-ZP101 | Dextran, Alexa Fluor® 555-Conjugated, 10,000 MW | Alexa Fluor® 555 | 555/565 | |
NTA-2011-ZP102 | Dextran, Alexa Fluor® 568-Conjugated, 10,000 MW | Rhodamine | Alexa Fluor® 568 | 578/603 |
NTA-2011-ZP103 | Dextran, Alexa Fluor® 594-Conjugated, 10,000 MW | Texas Red® | Alexa Fluor® 594 | 590/617 |
NTA-2011-ZP104 | Dextran, Alexa Fluor® 647-Conjugated, 10,000 MW | Cy®5 | Alexa Fluor® 647 | 650/668 |
NTA-2011-ZP105 | Dextran, Alexa Fluor® 680-Conjugated, 10,000 MW | Cy®5.5 | Alexa Fluor® 680 | 679/702 |
NTA-2011-ZP106 | Dextran, Tetramethylrhodamine and Biotin-Conjugated, 10,000 MW | TAMRA | TAMRA | 555/580 |
NTA-2011-ZP107 | Dextran, Fluorescein and Biotin-Conjugated, 10,000 MW | FITC | Fluorescein | 494/518 |
Cat. No. | Product Name | Ex/Em (nm) | MW g.mol-1 |
NTA-2011-ZP108 | Dextran-amine |
3 000 5 000 10 000 40 000 70 000 500 000 2 000 000 |
|
NTA-2011-ZP109 | Dextran-Blue (Cibacron blue F3GA) | 621.5 / - |
5 000 10 000 70 000 110 000 500 000 2 000 000 |
NTA-2011-ZP110 | Dextran–FITC | 494/518 |
3 000 4 000 10 000 20 000 40 000 70 000 500 000 |
NTA-2011-ZP111 | Dextran-FITC, Lysine Fixable | 494/518 |
3 000 4 000 10 000 20 000 40 000 70 000 500 000 |
NTA-2011-ZP112 | Dextran–biotin |
3 000 10 000 40 000 70 000 500 000 |
|
NTA-2011-ZP113 | Dextran-biotin, Lysine Fixable |
3 000 10 000 40 000 70 000 500 000 |
|
NTA-2011-ZP114 | Dextran–Rhodamine B | 555/580 |
3 000 10 000 40 000 70 000 500 000 |
NTA-2011-ZP115 | Dextran-TMR, Lysine Fixable | 555/580 |
3 000 10 000 40 000 70 000 500 000 |
NTA-2011-ZP116 | Dextran-TRITC | 555/580 | 4 000 |
NTA-2011-ZP117 | Dextran-CYanine5 | 580/675 |
3 000 10 000 40 000 70 000 500 000 |
NTA-2011-ZP118 | Dextran-CYanine5.5 | 663/690 |
3 000 10 000 40 000 70 000 500 000 |
NTA-2011-ZP119 | Dextran-CYanine7 | 743/767 | 8 000 |
In addition to reactive dye formulations, we also provide dyes conjugated with a variety of antibodies, peptides, proteins, tracers and amplification substrates to optimize cell labeling and detection. Please contact us for more details.
![](static/images/loading3.gif)
![](static/images/product/product-icon-neural-tracers.png)
![HOT](../static/images/hot.gif)
- Tracer Type:
- Dextan Conjugate
- Applications:
- Neural Tracing
![](static/images/product/product-icon-neural-tracers.png)
![HOT](../static/images/hot.gif)
- Tracer Type:
- Dextan Conjugate
- Applications:
- Neural Tracing
![](static/images/product/product-icon-neural-tracers.png)
- Tracer Type:
- Dextan Conjugate
- Applications:
- Neural Tracing
![](static/images/product/product-icon-neural-tracers.png)
- Tracer Type:
- Dextan Conjugate
- Applications:
- Neural Tracing
![](static/images/product/product-icon-neural-tracers.png)
- Tracer Type:
- Dextan Conjugate
- Applications:
- Neural Tracing
![](static/images/product/product-icon-neural-tracers.png)
- Tracer Type:
- Dextan Conjugate
- Applications:
- Neural Tracing
![](static/images/product/product-icon-neural-tracers.png)
- Tracer Type:
- Dextan Conjugate
- Applications:
- Neural Tracing
![](static/images/product/product-icon-neural-tracers.png)
- Tracer Type:
- Dextan Conjugate
- Applications:
- Neural Tracing
![](static/images/product/product-icon-neural-tracers.png)
- Tracer Type:
- Dextan Conjugate
- Applications:
- Neural Tracing
![](static/images/product/product-icon-neural-tracers.png)
- Tracer Type:
- Dextan Conjugate
- Applications:
- Neural Tracing
![](static/images/product/product-icon-neural-tracers.png)
- Tracer Type:
- Dextan Conjugate
- Applications:
- Neural Tracing
![](static/images/product/product-icon-neural-tracers.png)
- Tracer Type:
- Dextan Conjugate
- Applications:
- Neural Tracing