Lumbar Disk Disease Related Research Tools
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Lumbar disk disease (Herniated Disk), a major cause of lower back pain, is the drying out of the spongy interior matrix of an intervertebral disc in the spine. It is also known as lumbar spondylosis. Pain, loss of muscle strength and loss of touch sensation may occur in patients with lumbar disk disease. In severe cases, a herniated disc can produce a dysfunction of the nerve.
Lumbar disk disease is caused by a change in the structure of the normal disk. Most of the time, lumbar disk disease results from aging. However, an inheritable gene variation may cause increased susceptibility. Cartilage intermediate-layer protein (CILP) is a normal component of the disk tissue. The CILP variant is hypothesized to disrupt the normal building and maintenance of the cartilage. People with CILP mutant are 1.6 times more likely to develop the disease.
Creative Biolabs has a comprehensive list of bio-reagents involving in lumbar disk disease (herniated disk) research. The following is a part of our featured products that may be associated with your areas of interest.
- Neural Cell Lines
- Basal Media
- Media Supplements
- Specialty Media
- Cell Differentiation Media
- Cell Dyes
- Neural Cell Culture Antibiotics
- Assay Kits
- Buffers & Solutions
- Neural Antibodies
- Recombinant Proteins
- Cytokines
- Growth Factors
- Small Molecules
- Toxins
- Agonists
- Antagonists
- Animal Models
- Tools & Devices
Creative Biolabs appreciates the critical roles that our products play in research efforts to further Lumbar disk disease (Herniated disk) diagnosis and treatment.
Pathways Related to Creative Biolabs Products of Lumbar Disk Disease (Herniated Disk)
| Super pathways | Genes |
| ERK signaling | IL6, IL1B, IL1A, COL9A3, COL9A2, COL11A2 |
| Phospholipase-C pathway | IL6, COL9A3, COL9A2, COL11A2, COL11A1 |
| Focal adhesion | THBS2, COL9A3, COL9A2, COL11A2, COL11A1 |
| Collagen chain trimerization | MMP9, COL9A3, COL9A2, COL11A2, COL11A1 |
| Degradation of the extracellular matrix | MMP9, COL9A3, COL9A2, COL11A2, COL11A1, ASPN |
| T cell receptor signaling pathway | IL6, IL1B, IL1A, IFNG |
| IL-17 family signaling pathway | MMP9, IL6, IL1B, IFNG |
| Toll comparative pathway | IL6, IL1B, IL1A, IFNG |
For Research Use Only. Not For Clinical Use.
Target
Related Products
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NeuroMab™ Mouse Anti-IL1A Monoclonal Antibody (CBP6480) [CAT#: NAB-1021-R0349]
Mouse monoclonal to IL1A
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IHC; ICC; IF
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3304
NeuroMab™ Mouse Anti-IL1A Monoclonal Antibody (CBP5310) [CAT#: NAB-0321-R0760]
Mouse Monoclonal to IL1A
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IF; IHC; WB
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2947
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