Microglia Products

Microglia are often referred to as the "guardians" of the brain. They constantly monitor and adjust the brain's environment, responding to injury, infection, and inflammation. Their primary functions include the removal of debris, support of neurons, and regulation of neuroinflammation. A variety of recent research investigations have underscored the significant importance of microglial cells in the context of neurological diseases. At Creative Biolabs, we are committed to advancing neuroscience by offering premium microglia cell products specifically designed for researchers.

Product Overview

	Primary Microglia Human microglia (NCL-21P6-039) Mouse Microglia from C57BL/6 (NCL-21P6-082) Rat Microglia (NCL-21P6-083)
	Immortalized Microglia Mouse Microglia BV-2 (NCL2110P153) Mouse Microglia N9 (NCL2110P073) Human Microglia HMC3 (NCL-2108P38) Rat Microglia HAPI (NCL2110P015)
	Human iPSC-derived Microglia iNeu™ Microglia iNeu™ Human Microglia - Alzheimer's Disease iNeu™ Human Microglia - Parkinson's Disease iNeu™ Human Microglia - Epilepsy iNeu™ Human Microglia - Autism Spectrum Disorder

Applications

Microglia are essential for modulating neuroinflammatory responses, supporting neuronal health, and regulating synaptic connections. Microglia cell products have various applications in vitro research:

• Neuroinflammation Studies: Microglia serve as the primary immune responders in the central nervous system and play a crucial role in regulating neuroinflammation. Researchers can use these products to explore phagocytosis, inflammasome, cytokine release and NO/ROS release.
• Neurodevelopment: Microglia influence neuronal development and synaptic pruning. Exosomes and signaling molecules secreted by microglia aid in understanding their role during critical periods of brain development.
• Disease Modeling: Disease-derived or stimulus-induced microglial products can be utilized in generating in vitro models of diseases like Alzheimer's and multiple sclerosis, allowing for the investigation of disease mechanisms and potential therapeutic targets.
• Microglia Migration: I Microglia migration is crucial in research as it helps elucidate their role in brain development, immune response, and neurodegenerative diseases. Understanding their migration patterns can inform therapeutic strategies for conditions like Alzheimer's and multiple sclerosis, enhancing targeted treatments.
• Drug Discovery: Compounds that modulate microglial activity are being explored for neuroprotective effects. Screening for these compounds can lead to novel treatments for neurodegenerative disorders.

Features & Advantages

Related Services

We are excited to offer you the following microglia-related services utilizing our microglia products.

Reference

1. Bull, Daniel et al. "Generation of an hiPSC-Derived Co-Culture System to Assess the Effects of Neuroinflammation on Blood-Brain Barrier Integrity." Cells. 2022;11(3):419. Distributed under Open Access license CC BY 4.0 without modification.