Gene Therapy Tools
Creative Biolabs is a supplier of products designed for use in neuroscience research. We offer a variety of neuroscience research tools and services, covering areas such as basic research, neurological diseases, neural cell culture, and neural model construction. After extensive product development, we are pleased to announce the launch of several new tools for gene silencing and expression. Our products will assist you in achieving your research objectives, whether you are looking to knock out, knock in, knock down, or overexpress your target.
We are always expanding the product list. Please contact us and tell us your requirements and we'll customize the products according to your needs.
Product Overview
Advances in genome engineering, from the study of disease mechanisms to drug development, are enabling researchers to make unprecedented breakthroughs in neurological disorders. Our selection comprises, but is not restricted to:
- RNAi Substrates: We provide three types of small RNAs for RNAi: short hairpin RNA (shRNA), small interfering RNA (siRNA), and microRNA (miRNA). Creative Biolabs offers an extensive selection of products for many popular targets in neurological disorders, such as APOE, Tau, SOD1, CTNNB1, Huntingtin and others. We can also tailor RNAi solutions to match your specific requirements.
- Gene Expression Vectors: With our ready-to-use expression vectors, you can skip the time-consuming cloning, validation, and sequence analysis steps. We provide an array of expression systems, promoter clones, fusion tags and screening markers, and you can customize or purchase pre-made, ready-to-use expression vectors.
- Antisense Oligonucleotides (ASOs): We now have a list of ready-to-use ASO products for research into a number of neurological disorders. If you have identified a prospective RNA target and are looking for the best ASO, we can provide a customized solution.
- Viral Tracers: Viral products play a pivotal role in gene therapy, particularly as gene delivery vectors. By engineering viruses to remove their pathogenicity while preserving their delivery capabilities, viral vectors have become a cornerstone of gene therapy.
Advantages
- Strict quality control and cost-effective.
- Available on request for flexible synthesis sizes and bulk orders.
- Cover several kinds of targets for neurological disorders.
Trending Products
Alzheimer's Disease
Cat# | Product Name | Target |
NV-2106-P27 | ABCA1 Antisense Oligonucleotide (AK311445) | ABCA1 |
NEP-0421-R0053 | App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged | App |
NEP-0421-R0232 | Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged | APOE |
NEP-0421-R0140 | Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged | PSEN1 |
NV-2106-P29 | Tau Antisense Oligonucleotide (IONIS-MAPTRx) | Tau |
Parkinson's Disease
Cat# | Product Name | Target |
NEP-0521-R0864 | Lenti of Mouse synuclein, alpha (Snca) transcript variant (NM_001042451) ORF clone, mGFP Tagged | SNCA |
NEP-0621-R0133 | Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged | PARK7 |
NEP-0621-R0041 | Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged | PARK2 |
Amyotrophic Lateral Sclerosis
Cat# | Product Name | Target |
NEP-0521-R0748 | Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged | SOD1 |
NEP-0521-R0808 | Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged | SOD3 |
NEP-0521-R0832 | Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged | TARDBP |
NV-2106-P14 | Mouse SOD1 shRNA Silencing Adenovirus | SOD1 |
Huntington's Disease
Cat# | Product Name | Target |
NEP-0521-R0497 | Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged | HTT |
NEP-0521-R0676 | Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged | HAP1 |
Target
Expression Vectors


- Applications:
- Our Dystrophin, exon 45-ASO targets a specific exon of the Dystrophin gene, important for studying Duchenne Muscular Dystrophy. It enables investigation of how exon 45 - related Dystrophin abnormalities affect neural - muscle communication, nerve - mediated muscle function, and the underlying neurological aspects of the disease.

- Applications:
- Our Dystrophin, exon 53-ASO targets a specific exon of the Dystrophin gene, crucial for understanding Duchenne Muscular Dystrophy. It allows for the study of how exon 53 - related Dystrophin abnormalities affect neural - muscle interactions, nerve - mediated muscle control, and the underlying neurological mechanisms of the disease.

- Applications:
- Designed to target exon 51 of the Dystrophin gene, our ASO is valuable for studying Duchenne Muscular Dystrophy. Beyond muscle effects, it aids in exploring how Dystrophin exon 51 dysregulation impacts neuromuscular junction signaling and nervous system development, contributing to a more comprehensive understanding of the disease and potential therapeutic strategies.

- Applications:
- Our DMD-ASO is designed to target the Duchenne Muscular Dystrophy (DMD) gene. While primarily associated with muscle pathology, it also aids in exploring the impact of DMD gene dysregulation on neuromuscular junction function and potential secondary effects on the nervous system, providing insights into the broader disease mechanisms and possible neurological interventions.
- iNeuMab™ Anti-FGFR1 Antibody (NRP-0422-P1244) (Cat#: NRP-0422-P1244)
- iNeuMab™ Anti-Integrin αvβ8 BBB Shuttle Antibody (NRZP-1222-ZP1218) (Cat#: NRZP-1222-ZP1218)
- iNeuMab™ Anti-ApoC3 BBB Shuttle Antibody (NRZP-1022-ZP3505) (Cat#: NRZP-1022-ZP3505)
- iNeuMab™ Anti-GARP Antibody (NRP-0422-P1639) (Cat#: NRP-0422-P1639)
- iNeuMab™ Anti-Tau Antibody (NRP-0422-P1686) (Cat#: NRP-0422-P1686)
- iNeuMab™ Anti-CD20 Antibody (NRP-0422-P1230) (Cat#: NRP-0422-P1230)
- iNeuMab™ Anti-TNFα BBB Shuttle Antibody (NRZP-1022-ZP4105) (Cat#: NRZP-1022-ZP4105)
- iNeuMab™ Anti-F-Spondin/SPON1 Antibody, Clone 3F4 (Cat#: NRZP-0822-ZP4740)
- iNeuMab™ Mouse Anti-SHANK3 Monoclonal Antibody (CBP929) (Cat#: NAB-0720-Z3477)
- iNeuMab™ Anti-Tau Antibody (NRP-0422-P2275) (Cat#: NRP-0422-P2275)
- iNeu™ Human Sensory Neurons (Cat#: NCL-2103-P62)
- iNeu™ Human Neural Stem Cell Line (Cat#: NCL200552ZP)
- Human Brain Microvascular Endothelial Cells (Cat#: NCL-2103-P133)
- Human Microglia Cell Line HMC3, Immortalized (Cat#: NCL-2108P38)
- Mouse Retinal Ganglion Cell Line RGC-5 (Cat#: NCL2110P154)
- Mouse Microglia N9 (Cat#: NCL2110P073)
- Human Astrocytes (Cat#: NCC20-9PZ01)
- Mouse Glioma Cell Line GL261 (Cat#: NCL-2108P28)
- Mouse Midbrain Dopaminergic Neuron Cell MN9D (Cat#: NCL2110P059)
- Human Brain Astroblastoma U-87 MG (Cat#: NCL2110P117)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- VSV-eGFP (Cat#: NTA-2011-ZP20)
- Dextran, NHS Activated (Cat#: NRZP-0722-ZP124)
- AAV2 Full Capsids, Reference Standards (Cat#: NTC2101070CR)
- Tau Antisense Oligonucleotide (IONIS-MAPTRx) (Cat#: NV-2106-P29)
- Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0676)
- Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0497)
- ABCA1 Antisense Oligonucleotide (NV-2106-P27) (Cat#: NV-2106-P27)
- Lenti of Mouse synuclein, alpha (Snca) transcript variant (NM_001042451) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0864)
- App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged (Cat#: NEP-0421-R0053)
- Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged (Cat#: NEP-0621-R0133)
- Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged (Cat#: NEP-0421-R0232)
- Mouse SOD1 shRNA Silencing Adenovirus (Cat#: NV-2106-P14)
- Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0832)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroPro™ Anti-PON1 BBB Shuttle Protein (Cat#: NRZP-0423-ZP507)
- NeuroPro™ Anti-SGSH BBB Shuttle Protein (Cat#: NRZP-0423-ZP505)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP500)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP510)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP502)
- NeuroPro™ Anti-NAGLU BBB Shuttle Protein (Cat#: NRZP-0423-ZP506)
- NeuroPro™ Anti-EPO BBB Shuttle Protein (Cat#: NRZP-0423-ZP508)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP501)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP498)
- NeuroPro™ Anti-idursulfase BBB Shuttle Protein (Cat#: NRZP-0423-ZP497)