Gene Therapy Tools
Creative Biolabs is a supplier of products designed for use in neuroscience research. We offer a variety of neuroscience research tools and services, covering areas such as basic research, neurological diseases, neural cell culture, and neural model construction. After extensive product development, we are pleased to announce the launch of several new tools for gene silencing and expression. Our products will assist you in achieving your research objectives, whether you are looking to knock out, knock in, knock down, or overexpress your target.
We are always expanding the product list. Please contact us and tell us your requirements and we'll customize the products according to your needs.
Product Overview
Advances in genome engineering, from the study of disease mechanisms to drug development, are enabling researchers to make unprecedented breakthroughs in neurological disorders. Our selection comprises, but is not restricted to:
- RNAi Substrates: We provide three types of small RNAs for RNAi: short hairpin RNA (shRNA), small interfering RNA (siRNA), and microRNA (miRNA). Creative Biolabs offers an extensive selection of products for many popular targets in neurological disorders, such as APOE, Tau, SOD1, CTNNB1, Huntingtin and others. We can also tailor RNAi solutions to match your specific requirements.
- Gene Expression Vectors: With our ready-to-use expression vectors, you can skip the time-consuming cloning, validation, and sequence analysis steps. We provide an array of expression systems, promoter clones, fusion tags and screening markers, and you can customize or purchase pre-made, ready-to-use expression vectors.
- Antisense Oligonucleotides (ASOs): We now have a list of ready-to-use ASO products for research into a number of neurological disorders. If you have identified a prospective RNA target and are looking for the best ASO, we can provide a customized solution.
- Viral Tracers: Viral products play a pivotal role in gene therapy, particularly as gene delivery vectors. By engineering viruses to remove their pathogenicity while preserving their delivery capabilities, viral vectors have become a cornerstone of gene therapy.
Advantages
- Strict quality control and cost-effective.
- Available on request for flexible synthesis sizes and bulk orders.
- Cover several kinds of targets for neurological disorders.
Trending Products
Alzheimer's Disease
Cat# | Product Name | Target |
NV-2106-P27 | ABCA1 Antisense Oligonucleotide (AK311445) | ABCA1 |
NEP-0421-R0053 | App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged | App |
NEP-0421-R0232 | Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged | APOE |
NEP-0421-R0140 | Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged | PSEN1 |
NV-2106-P29 | Tau Antisense Oligonucleotide (IONIS-MAPTRx) | Tau |
Parkinson's Disease
Cat# | Product Name | Target |
NEP-0521-R0864 | Lenti of Mouse synuclein, alpha (Snca) transcript variant (NM_001042451) ORF clone, mGFP Tagged | SNCA |
NEP-0621-R0133 | Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged | PARK7 |
NEP-0621-R0041 | Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged | PARK2 |
Amyotrophic Lateral Sclerosis
Cat# | Product Name | Target |
NEP-0521-R0748 | Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged | SOD1 |
NEP-0521-R0808 | Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged | SOD3 |
NEP-0521-R0832 | Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged | TARDBP |
NV-2106-P14 | Mouse SOD1 shRNA Silencing Adenovirus | SOD1 |
Huntington's Disease
Cat# | Product Name | Target |
NEP-0521-R0497 | Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged | HTT |
NEP-0521-R0676 | Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged | HAP1 |
Target
Expression Vectors


Under standard conditions, at least one siRNA pair achieved an mRNA silencing efficiency exceeding 70%.
- Applications:
- Gene Silencing

- Applications:
- Our FOXP3-ASO targets Forkhead Box P3 (FOXP3), which is involved in regulatory T - cell function. In neuroscience, it allows researchers to investigate FOXP3's role in neuroimmune regulation, neuroinflammation, and autoimmune neurological diseases, facilitating the development of immunomodulatory therapies.
- iNeuMab™ Anti-TREM2 Antibody (NRP-0422-P792) (Cat#: NRP-0422-P792)
- iNeuMab™ Anti-TREM2 BBB Shuttle Antibody (NRZP-1022-ZP4114) (Cat#: NRZP-1022-ZP4114)
- iNeuMab™ Anti-ApoC3 BBB Shuttle Antibody (NRZP-1022-ZP3505) (Cat#: NRZP-1022-ZP3505)
- iNeuMab™ Rabbit Anti-LRRK2 Monoclonal Antibody (CBP1887) (Cat#: NAB-08-PZ735)
- iNeuMab™ Anti-SEZ6 Antibody (NRP-0422-P517) (Cat#: NRP-0422-P517)
- iNeuMab™ Anti-ApoC3 BBB Shuttle Antibody (NRZP-1022-ZP3503) (Cat#: NRZP-1022-ZP3503)
- iNeuMab™ Anti-TNFα BBB Shuttle Antibody (NRZP-1022-ZP4105) (Cat#: NRZP-1022-ZP4105)
- iNeuMab™ Anti-Integrin αvβ8 BBB Shuttle Antibody (NRZP-1222-ZP1218) (Cat#: NRZP-1222-ZP1218)
- iNeuMab™ Anti-Tau Antibody (NRP-0422-P2275) (Cat#: NRP-0422-P2275)
- iNeuMab™ Anti-EPHB2 Antibody (NRP-0422-P1220) (Cat#: NRP-0422-P1220)
- iNeu™ Human Motor Neurons (Cat#: NCL-2103-P71)
- iNeu™ Human Schwann Cell (Cat#: NCL-2103-P63)
- Green Fluorescent BACE1 Cell Lines (Cat#: NCL2110P214)
- Rat Muller Cell (Cat#: NCL2110P040)
- Rat Microglia Cell Line HAPI, Immortalized (Cat#: NCL2110P015)
- Human Brain Vascular Adventitial Fibroblasts (Cat#: NCL-21P6-014)
- Mouse Microglia from C57BL/6 (Cat#: NCL-21P6-082)
- iNeu™ Human Oligodendrocyte Progenitor Cells (OPCs) (Cat#: NCL-2103-P49)
- Rat Retinal Muller Cell Line, Immortalized (Cat#: NCL-21P6-192)
- Mouse Retinal Ganglion Cell Line RGC-5 (Cat#: NCL2110P154)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- VSV-eGFP (Cat#: NTA-2011-ZP20)
- Dextran, NHS Activated (Cat#: NRZP-0722-ZP124)
- AAV2 Full Capsids, Reference Standards (Cat#: NTC2101070CR)
- Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged (Cat#: NEP-0521-R0748)
- Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged (Cat#: NEP-0521-R0808)
- Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged (Cat#: NEP-0621-R0041)
- Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged (Cat#: NEP-0621-R0133)
- ABCA1 Antisense Oligonucleotide (NV-2106-P27) (Cat#: NV-2106-P27)
- Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0676)
- App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged (Cat#: NEP-0421-R0053)
- Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged (Cat#: NEP-0421-R0140)
- Tau Antisense Oligonucleotide (IONIS-MAPTRx) (Cat#: NV-2106-P29)
- Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0832)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroPro™ Anti-ASA BBB Shuttle Protein (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-NAGLU BBB Shuttle Protein (Cat#: NRZP-0423-ZP506)
- NeuroPro™ Anti-IDS BBB Shuttle Protein (Cat#: NRZP-0423-ZP503)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP500)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP510)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-EPO BBB Shuttle Protein (Cat#: NRZP-0423-ZP508)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP498)
- NeuroPro™ Anti-Erythropoietin BBB Shuttle Protein (Cat#: NRZP-0423-ZP499)
- NeuroPro™ Anti-SGSH BBB Shuttle Protein (Cat#: NRZP-0423-ZP505)