Neurological Disease-Related Cell Lines

Neurodegenerative diseases (for example, Alzheimer's disease, Parkinson's disease) and neurodevelopmental diseases are one of the major causes of human disability and death. Despite the rapid development of new diagnostic methods and treatment methods, there are no effective methods for preventing and curing these neurological diseases so far. The lack of in vitro models has limited the understanding and treatment of many diseases, especially due to the difficulties in culturing primary cells affected by the disease. Luckily, human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) provide important cell sources for in vitro studies. The system for neural cell differentiation of hESC and iPSC provides an experimental model that can facilitate in vitro studies of neurological diseases.

In view of this, Creative Biolabs has produced a number of different patient-specific iPSCs to mimic human neurodegenerative diseases, such as Parkinson's disease (PD), Huntington's disease (HD), amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD). These cells help to better understand the molecular mechanisms of the pathophysiology of many refractory neurodegenerative diseases, and are designed to help researchers develop effective therapies.

Please browse the options below to learn more about the cell line model of your interest.