Neuron Marker Related Research Reagents

Neurons are specialized cells of the central nervous system and the basic signal components of the brain. Neuronal dysfunction is an important factor in many neurological diseases. Therefore, the ability to identify, characterize, and analyze these different cells and their functions is essential for neuroscience and neuropathology research. Different neurons have different functions, and can be divided into several categories according to the neurotransmitters they express, their polarity, morphology, anatomical location, and the direction in which they transmit information.

Neurons are usually divided into the body (cell body), axon, dendrite and synapse. These unique compartments can be distinguished from different cell types in the nervous system using specific markers.

According to the polar states and anatomical positions, neurons can be divided into:

Overview of General Neuron Markers

A List of Neuron Markers Provided by Creative Biolabs

1. Cholinergic Neuron Markers

Subcellular Localization	Markers
Cytoplasmic	Acetylcholinesterase/ACHE	Choline Acetyltransferase/ChAT
Cell Surface	VAChT/SLC18A3

2. Dopaminergic Neuron Markers

Subcellular Localization	Markers
Nuclear	HNF-3b/FoxA2 LMX1b	Nurr1/NGFI-Bb/NR4A2
Cytoplasmic	Tyrosine Hydroxylase	Dopamine b-Hydroxylase
Cell Surface	FOLR1	SLC6A3/DAT1

3. GABAergic Neuron Markers

Subcellular Localization	Markers
Cytoplasmic	GAD1/GAD67	GAD2/GAD65
Cell Surface	GABAB R1 GABAB R2	GAT-1/SLC6A1 VIAAT/SLC32A1/VGA

4. Glutamatergic Neuron Markers

Subcellular Localization	Markers
Cytoplasmic	Glutamine Synthetase
Cell Surface	GRIN1/NMDAR1 GRIN2B/NMDAR2B	VGLUT1/SLC17A7 VGLUT2/SLC17A6

5. Glycinergic Neuron Markers

Subcellular Localization	Markers
Cell Surface	VIAAT/SLC32A1/VGAT

6. Serotonergic Neuron Markers

Subcellular Localization	Markers
Nuclear	Pet1
Cytoplasmic	Dopa Decarboxylase/DDC	Tryptophan Hydroxylase/TPH-1
Cell Surface	SLC6A4/5-HTTLPR/Serotonin Transporter	VMAT2

With our easy-to-use guide, make sure you choose the best cell marker tools for your research needs.

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NeuroMab™ Rabbit Anti-GAD65/GAD67 Monoclonal Antibody (CBP984) [CAT#: NAB-0720-Z3848]

GAD65 / GAD67 Rabbit Monoclonal Antibody

Host Species:

Rabbit

Species Reactivity:

Mouse; Rat; Human

Applications:

IP; IHC-P; IHC-Fr; WB; ICC; IF

Conjugation:

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1036

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