Potassium Channel Related Research Reagents

Potassium ion channels are the most widely distributed type of ion channels and are found in almost all living organisms. They form potassium-selective pores across cell membranes. Potassium ion channels are present in most cell types and control a variety of cell functions such as cognition, muscle contraction and hormone secretion. Therefore, abnormal function of potassium channels may lead to diseases (such as diabetes) and life-threatening arrhythmias. Potassium channels may also be involved in maintaining vascular tone.

There are four main types of potassium channels:

• Calcium-activated potassium channels - open in response to the presence of calcium ions.
• Inwardly rectifying potassium channels - pass current (positive charge) in the inward direction (into the cell).
• Tandem pore domain potassium channels - constitutively open or have a high degree of basic activation, such as "quiescent potassium channels" or "leak channels" that set the negative membrane potential of neurons.
• Voltage-gated potassium channels - voltage-gated ion channels that can open or close in response to changes in transmembrane voltage.

Potassium channel classes & functions

Creative Biolabs provides a variety of potassium channel blockers, which can prevent potassium ions from passing through the channels on the cell membrane, and are used to treat hypertension and epilepsy. Our product portfolio also includes a series of products for potassium channel receptors research, including monoclonal antibodies, labeled antibodies, proteins, assay kits, and small molecule activators and inhibitors.

Please browse the options to take a deeper look at the tools for your research needs.

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Mouse Anti-Kir2.1 Monoclonal Antibody (CBP2055) [CAT#: NAB2007FY703]

Mouse Monoclonal [NS112B-14] to Kir2.1

Host Species:

Mouse

Species Reactivity:

Human; Monkey; Mouse; Rat

Applications:

WB; IHC; ICC; IF; AM

Conjugation:

Alkaline Phosphatase; APC; APC/Cy7; ATTO 390; ATTO 488; ATTO 565; ATTO 594; ATTO 633; ATTO 655; ATTO 680; ATTO 700; Biotin; Dylight 350; Dylight 405; Dylight 488; Dylight 594; Dylight 633; FITC; HRP; PE/ATTO 604; PerCP; RPE; Streptavidin; Unconjugated

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Mouse Anti-KCNJ2 Monoclonal Antibody (CBP777) [CAT#: NAB-0720-Z3011]

Kir2.1/BIK Mouse Monoclonal Antibody

Host Species:

Mouse

Species Reactivity:

Mouse; Rat; Human

Applications:

WB; ICC; IF; IHC-P; FC

Conjugation:

Unconjugated

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NeuroMab™ Rabbit Anti-KCNJ2 Monoclonal Antibody (CBP774) [CAT#: NAB-0720-Z3007]

Kir2.1/BIK Rabbit Monoclonal Antibody

Host Species:

Rabbit

Species Reactivity:

Mouse; Rat; Human

Applications:

ICC; IF; WB; IHC-P

Conjugation:

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 891

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Datasheet MSDS