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Creative Biolabs

Potassium Channel Related Research Reagents

Potassium Channels

Potassium ion channels are the most widely distributed type of ion channels and are found in almost all living organisms. They form potassium-selective pores across cell membranes. Potassium ion channels are present in most cell types and control a variety of cell functions such as cognition, muscle contraction and hormone secretion. Therefore, abnormal function of potassium channels may lead to diseases (such as diabetes) and life-threatening arrhythmias. Potassium channels may also be involved in maintaining vascular tone.

There are four main types of potassium channels:

Potassium channel classes & functions

Class Subclasses Function Blockers Activators
Calcium-activated
  • BK channel
  • SK channel
  • IK channel
  • inhibition in response to rising intracellular calcium
  • Charybdotoxin
  • Iberiotoxin
  • Apamin
  • BKCa-specific
  • GAL-021
  • EBIO
  • NS309
  • CyPPA
  • Flufenamic acid
  • Meclofenamic acid
  • Niflumic acid
  • Nimesulide
  • Rottlerin (mallotoxin)
  • Tolfenamic acid
Inwardly rectifying
  • ROMK (Kir1.1)
  • GPCR regulated (Kir3.x)
  • ATP-sensitive (Kir6.x)
  • recycling and secretion of potassium in nephrons
  • mediate the inhibitory effect of many GPCRs
  • close when ATP is high to promote insulin secretion
  • Ifenprodil
  • Cloperastine
  • Tertiapin
  • Tipepidine
  • Acetohexamide
  • Carbutamide
  • Chlorpropamide
  • Glibenclamide (glyburide)
  • Glibornuride
  • Glicaramide
  • Gliclazide
  • Glimepiride
  • Glipizide
  • ML-297 (VU0456810)
  • Bimakalim
  • Cromakalim
  • Diazoxide
  • Levcromakalim
  • Minoxidil
  • Nicorandil
  • Pinacidil
Tandem pore domain
  • TWIK (TWIK-1, TWIK-2, KCNK7)
  • TREK (TREK-1, TREK-2)
  • TASK (TASK-1, TASK-3, TASK-5)
  • TALK (TASK-2, TALK-1, TALK-2)
  • THIK (THIK-1, THIK-2)
  • TRESK
  • Contribute to resting potential
  • Bupivacaine
  • Quinidine
  • 12-O-Tetradecanoylphorbol-13-acetate
  • Arachidonic acid
  • Fluoxetine
  • Norfluoxetine
  • Modulated by GPCR agonists and antagonists
  • Halothane
  • Riluzole
  • Volatile anaesthetics
  • GPCR agonists and antagonists
Voltage-gated
  • hERG (Kv11.1)
  • KvLQT1 (Kv7.1)
  • action potential repolarization
  • limits the frequency of action potentials (disturbances cause dysrhythmia)
  • 3,4-Diaminopyridine (amifampridine)
  • 4-Aminopyridine (fampridine/dalfampridine)
  • Bretylium
  • Tetraethylammonium
  • Ajmaline
  • Amiodarone
  • AmmTX3
  • Linopirdine
  • Ssm spooky toxin
  • Flupirtine
  • Retigabine (Kv7)

Creative Biolabs provides a variety of potassium channel blockers, which can prevent potassium ions from passing through the channels on the cell membrane, and are used to treat hypertension and epilepsy. Our product portfolio also includes a series of products for potassium channel receptors research, including monoclonal antibodies, labeled antibodies, proteins, assay kits, and small molecule activators and inhibitors.

Please browse the options to take a deeper look at the tools for your research needs.

For Research Use Only. Not For Clinical Use.

Target

Tandem Pore Domain Potassium Channel Related Research Reagents

Inwardly Rectifying Potassium Channel Related Research Reagents

Voltage-gated Potassium Channel Related Research Reagents

Calcium-activated Potassium Channel Related Research Reagents

Related Products
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Target: KCNQ2

Anti-KCNQ2 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
Applications:
IHC-P; ICC; WB
Conjugation:
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 3028

Mouse Monoclonal [NS26A-23] to KCNQ2

Host Species:
Mouse
Species Reactivity:
Hamster; Human; Mouse; Rat
Applications:
WB; IHC; ICC; IF; IP; AM
Conjugation:
Alkaline Phosphatase; APC; APC/Cy7; ATTO 390; ATTO 488; ATTO 565; ATTO 594; ATTO 633; ATTO 655; ATTO 680; ATTO 700; Biotin; Dylight 350; Dylight 405; Dylight 488; Dylight 594; Dylight 633; FITC; HRP; PE/ATTO 604; PerCP; RPE; Streptavidin; Unconjugated

KCNQ2 Mouse Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Mouse; Rat; Human
Applications:
IHC-P; IHC-Fr; ICC; IF; IP; WB; FC
Conjugation:
Unconjugated
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