Creative Biolabs

Chicago Sky Blue 6B [counterstain for background autofluorescence]

[CAT#: NTA-2101-ZP37]

Counterstain for background autofluorescence. Allosteric MIF inhibitor. VGLUT inhibitor.

Biological Activity:
Counterstain the background autofluorescence. Allosteric MIF inhibitor. VGLUT inhibitor. Inhibit the MIF-directed pro-inflammatory activity. Effectively inhibit the uptake of L-glutamate into synaptic vesicles. Centrally active.

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Synonyms
Counterstain for background autofluorescence. Allosteric MIF inhibitor. VGLUT inhibitor.
Chemical Name
(6E)-4-Amino-6-[[4-[4-[(2Z)-2-(8-amino-1-oxo-5,7-disulfonatonaphthalen-2-ylidene)hydrazinyl]-3-methoxyphenyl]-2-methoxyphenyl]hydrazinylidene]-5-oxonaphthalene-1,3-disulfonate tetrasodium salt
Biological Activity
Counterstain the background autofluorescence. Allosteric MIF inhibitor. VGLUT inhibitor. Inhibit the MIF-directed pro-inflammatory activity. Effectively inhibit the uptake of L-glutamate into synaptic vesicles. Centrally active.
Modulator Type
Inhibitor
Applications
Ion Indicator
Molecular Weight
992.79
Form
Form / State: Solid
Chemical Formula
C34H24N6Na4O16S4
Source
Synthetic
SMILES
COC1=C(C=CC(=C1)C2=CC(=C(C=C2)NN=C3C=CC4=C(C3=O)C(=C(C=C4S(=O)(=O)[O-])S(=O)(=O)[O-])N)OC)NN=C5C=CC6=C(C5=O)C(=C(C=C6S(=O)(=O)[O-])S(=O)(=O)[O-])N.[Na+].[Na+].[Na+].[Na+]
Solubility
Soluble in water to 10 mM
CAS NO.
CAS Number: 2610-05-1
PubChem Substance ID
5359775
Purity
Purity:> 80%
Storage
Store at Room Temperature. The product can be stored for up to 12 months.
Handling Advice
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
For Research Use Only. Not For Clinical Use.
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