Creative Biolabs

Congo Red [Amyloid fibril-binding dye]

[CAT#: NTA-2101-ZP40]

Amyloid fibril-binding dye. Caspase inhibitor.

Biological Activity:
Amyloid fibrils bind dyes. Caspase inhibitor. Red moves on the aggregate and binds to amyloid fibrils. The blue shifts to the combination with cellulose. In the presence of amyloid fibrils polarized light shows apple green birefringence. Inhibit Fib-βA neurotoxicity.

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Synonyms
Amyloid fibril-binding dye. Caspase inhibitor.
Chemical Name
4-Amino-3-[[4-[4-[(1-amino-4-sulfonatonaphthalen-2-yl)diazenyl]phenyl]phenyl]diazenyl]naphthalene-1-sulfonate disodium salt
Biological Activity
Amyloid fibrils bind dyes. Caspase inhibitor. Red moves on the aggregate and binds to amyloid fibrils. The blue shifts to the combination with cellulose. In the presence of amyloid fibrils polarized light shows apple green birefringence. Inhibit Fib-βA neurotoxicity.
Modulator Type
Inhibitor
Applications
Ion Indicator
Molecular Weight
696.66
Form
Form / State: Solid
Excitation
497nm
Emission
614nm
Chemical Formula
C32H22N6Na2O6S2
Source
Synthetic
SMILES
C1=CC=C2C(=C1)C(=CC(=C2N)N=NC3=CC=C(C=C3)C4=CC=C(C=C4)N=NC5=C(C6=CC=CC=C6C(=C5)S(=O)(=O)[O-])N)S(=O)(=O)[O-].[Na+].[Na+]
Solubility
Soluble in water to 5 mM and in DMSO to 5 mM
CAS NO.
CAS Number: 573-58-0
PubChem Substance ID
11313
Purity
Purity:> 98%
Storage
Store at Room Temperature. The product can be stored for up to 12 months.
Handling Advice
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
For Research Use Only. Not For Clinical Use.
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