Elastase Substrate [Fluorogenic (MeOSuc-AAPV-AFC)]
[CAT#: NTA-2101-ZP18]
Highly sensitive coumarin-fluorogenic substrate for neutrophil elastase
- Biological Activity:
- Highly sensitive coumarin fluorescent substrate for neutrophil elastase (Km of leukocyte elastase = 130 µM). Compatible with in vitro assays of purified enzymes in live cells or conditioned media. The excitation wavelength is 380nm and the emission wavelength is 500nm.
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Synonyms
Highly sensitive coumarin-fluorogenic substrate for neutrophil elastase
Chemical Name
N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-7-amino-4-trifluormethylcoumarin
Biological Activity
Highly sensitive coumarin fluorescent substrate for neutrophil elastase (Km of leukocyte elastase = 130 µM). Compatible with in vitro assays of purified enzymes in live cells or conditioned media. The excitation wavelength is 380nm and the emission wavelength is 500nm.
Applications
Ion Indicator
Molecular Weight
681.67
Form
Form / State: Solid
Chemical Formula
C31H38F3N5O9
Source
Synthetic
SMILES
O=C(OC)CCC(=O)NC(C)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)Nc2ccc3c(c2)OC(=O)C=C3C(F)(F)F
Solubility
Soluble in DMSO
Purity
Purity:> 99%
Storage
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling Advice
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
For Research Use Only. Not For Clinical Use.
