Epilepsy Drug Discovery Platform

Epilepsy is one of the most common and most disabling chronic neurologic disorders. People with epilepsy have recurrent unprovoked (spontaneous) seizures, which can be focal or generalized in nature. Seizures cannot be fully controlled in about a third of people with epilepsy. Developing novel drugs and management strategies for epilepsy has been a longstanding goal set by global neuroscientists.

For almost two decades, Creative Biolabs has been working to serve global biologists through cutting-edge technologies, and our specialized scientific research teams and customized quality services have been widely praised by global clients. Here, we would like to emphasize our Epilepsy drug discovery platform for neuroscientists worldwide.

Models of Epilepsy

Models have significantly contributed to our current understanding of the mechanisms of epilepsy, analysis of epilepsy-associated molecular, cellular, and network alterations, and their association with drug responsiveness for the development of novel drugs. Models approaches allow insights into mechanisms of epileptogenesis, Creative Biolabs can customize the most appropriate in vitro and in vivo models for preclinical antiepileptic drug screening based on your different needs.

Live cell tagged with tdTomato, and neurons expressing NeuN (green) in a mouse model of epilepsy. (Burnsed, 2019)

Experiments in Epilepsy Assay

Creative Biolabs has extensive experience and expertise in the epilepsy-related assay in vitro, ex vivo, and in vivo. We offer the following services to global researchers.

Perhaps you need to know something else? Please contact us directly for more information and we look forward to discussing it with you.

Reference

1. Burnsed, J.; et al. Neuronal Circuit Activity during Neonatal Hypoxic-Ischemic Seizures in Mice. Ann Neurol. 2019, 12, 86(6), 927-938.