Creative Biolabs

Fasudil [ROCK inhibitor]

[CAT#: NMO1120FY040]

ROCK inhibitor

Target:
ROCK

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Research Areas
Neurodegeneration
Relevant Disease
Parkinson's Disease
References
1. Shirotani M., et al. (1991) J. Pharmacol. Exp. Ther. 259(2): 738-744.
2. Arai M., Nozawa R., et al. (1993) Biochem. Pharmacol. 46(8): 1487-1490.
3. Satoh S., et al. (1996) Br. J. Pharmacol. 118(7): 1592-1606.
4. Sward K., et al. (2000) J. Physiol. 522: 33-49.
Molecular Weight
327.83
Form
Powder
Chemical Formula
C14H17N3O2S•HCl
Source
Synthetic
SMILES
C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3
Solubility
May be dissolved in DMSO (75 mg/ml) or water (100 mg/ml)
CAS NO.
103745-39-7
PubChem Substance ID
3547
Purity
>98% (HPLC); NMR (conforms)
Storage
-20°C
Shipping
Shipped Ambient
Research Use Only
For research use only
Target
ROCK
Official Name
ROCK
Full Name
Rho-Associated Protein Kinase 1
Alternative Names
1-(5-Isoquinolinylsulfonyl) homopiperazine hydrochloride; 5-(1,4-Diazepan-1-ylsulfonyl)isoquinoline
Gene ID
6093(Human); 19877(Mouse); 81762(Rat)
Uniprot ID
Q13464(Human); P70335(Mouse); Q63644(Rat)
For Research Use Only. Not For Clinical Use.
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