Gq Signaling Sensor cOpn5

[CAT#: NRZP-0822-ZP203]

Tracer Type:: Optogenetics

Applications:: Optogenetics

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Description

Gq-type G protein-coupled receptors (GPCRs) mediate the effects of a variety of external stimuli on eukaryotic cells and are potential drug targets, but can precisely control the light of the Gq signaling pathway in both temporal and spatial dimensions Genetic tools have been lacking. Therefore, developing an optogenetic tool that can precisely control the Gq signaling pathway is an important and challenging scientific problem.

Creative Biolabs provides a novel Gq signaling pathway sensor Chicken opsin 5 (cOpn5). cOpn5 is a light-supersensitive, plug-and-play, single-element photoreceptor capable of controlling cellular Gq signaling at extremely high temporal and spatial resolution and serves as an ideal Optogenetic tools study the function and mechanism of Gq-coupled receptors that are ubiquitous in cells.