Product
Human Anti-DJ-1 (CBP1952)
[CAT#: NAB2007FY442]
Human Monoclonal [W0042] to DJ-1 (Oxidized At C106)
- Host Species:
- Human
- Species Reactivity:
- Human
- Applications:
- ELISA; WB
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The human anti-human DJ-1 antibody, clone AbD03055, recognizes the human DJ-1 oncogene only when it is oxidized on cysteine C106. DJ-1 plays a role in transcriptional regulation and anti-oxidative stress response. The oxidation state of DJ-1, especially at C106, can adjust the function of DJ-1 (Canet-Avilés et al., 2004). DJ-1 oxidative disorder seems to be related to the onset of diseases such as Parkinson's disease.
Immunogen
The DJ-1 peptide is oxidized at C106 (sequence LIAAIC(SO3)AGPTA).
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Human
Isotype
HuCAL Fab bivalent
Clone Number
CBP1952
Applications
ELISA; WB
Relevant Diseases
Parkinson's Disease
Research Areas
Neuroregeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS; 0.01% Thiomersal
Preservatives
Yes
Concentration
0.5 mg/ml
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at +4°C or at -20°C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Andres-Mateos, E. et al. (2007) DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase.
2. Bitar, M.S. et al. (2012) Decline in DJ-1 and decreased nuclear translocation of Nrf2 in Fuchs endothelial corneal dystrophy.
3. Zhang C et al. (2008) Role of NonO-histone interaction in TNFalpha-suppressed prolyl-4-hydroxylase alpha1.
2. Bitar, M.S. et al. (2012) Decline in DJ-1 and decreased nuclear translocation of Nrf2 in Fuchs endothelial corneal dystrophy.
3. Zhang C et al. (2008) Role of NonO-histone interaction in TNFalpha-suppressed prolyl-4-hydroxylase alpha1.
Publications
Publications (0)
Neural Genes
Neural Cell Lines
Neural Antibodies
Kits
For Research Use Only. Not For Clinical Use.
