In Vitro Services
In the pursuit of understanding the brain's complexities and developing treatments for neurological disorders, in vitro services serve as the cornerstone of modern neuroscience research. They provide controlled, highly-defined environments for investigating cellular mechanisms, modeling devastating diseases, and screening for novel therapeutic candidates. Creative Biolabs offers a comprehensive, integrated suite of in vitro services, combining state-of-the-art technology with deep scientific expertise to propel your research from concept to clinic.
Explore Our In Vitro Services:
- Cell Culture Models
- CNS Cell-based Assays
- Neurological Disease related Assays
- Custom NeuroAntibody Development
- Neurological Cell Characterization
The foundation of any successful in vitro study is a well-characterized and appropriate cell model. We provide an extensive portfolio of neural cell culture systems, including primary cells that closely mimic the in vivo environment, infinitely scalable immortalized cell lines, and patient-specific human iPSC-derived models. By offering tailored cell models, including those for specific neurodegenerative diseases and complex organotypic slices, we ensure your experiments begin with the most relevant biological system possible.
Using highly relevant neurons, astrocytes, microglia, and oligodendrocytes, we perform a variety of assays to investigate core neural functions. These include assessments of neurotoxicity, neurite outgrowth, synaptogenesis, myelination, and glial cell activity, providing key insights into the fundamental processes of the central nervous system.
Neurological Disease related Assays
We have established a suite of sophisticated, disease-specific assays to model conditions like Alzheimer's, Parkinson's, and Multiple Sclerosis. These platforms enable the study of key pathological events—such as Aβ-induced toxicity, α-synuclein aggregation, and demyelination—and serve as powerful tools for evaluating the efficacy of potential new drugs.
Custom NeuroAntibody Development
High-quality antibodies are critical reagents for neuroscience research. We specialize in the custom development of highly specific and rigorously validated antibodies against challenging neurological targets, including ion channels, G-protein coupled receptors, and disease biomarkers like Tau and α-synuclein. Our neuroantibodies are optimized for a range of applications, including Western Blot, immunohistochemistry (IHC), and ELISA, providing the precision tools you need to accurately detect and quantify your targets of interest.
Neurological Cell Characterization
To ensure the validity and reproducibility of your results, rigorous characterization of your cell models is essential. We provide comprehensive characterization services to confirm cellular identity, purity, and the expression of key functional and disease-relevant markers. Leveraging techniques such as multi-color flow cytometry, immunocytochemistry (ICC), Western Blot, and qPCR, we deliver a complete profile of your neural cells, giving you full confidence in your experimental foundation.
Our General Workflow
By seamlessly integrating these services, Creative Biolabs provides a singular, expert partner for your neuroscience research. Our goal is to accelerate your discoveries and help translate them into the next generation of neurological therapies.
Partner with us to advance your research. Contact our team of specialists today to discuss your project.
- iNeuMab™ Rabbit Anti-LRRK2 Monoclonal Antibody (CBP1887) (Cat#: NAB-08-PZ735)
- Mouse Anti-Human α-Synuclein Phospho (Tyr39) (CBP3706) (Cat#: NAB201250LS)
- iNeuMab™ Mouse Anti-EFNB2 Monoclonal Antibody (CBP1159) (Cat#: NAB-0720-Z4396)
- iNeuMab™ Rabbit Anti-Alpha-synuclein (CBP1631) (Cat#: NAB-08-PZ079)
- iNeuMab™ Mouse Anti-LRP1 Monoclonal Antibody (CBP3363) (Cat#: NAB-0720-Z6479)
- iNeuMab™ Mouse Anti-SHANK3 Monoclonal Antibody (CBP929) (Cat#: NAB-0720-Z3477)
- iNeuMab™ Anti-F-Spondin/SPON1 Antibody, Clone 3F4 (Cat#: NRZP-0822-ZP4740)
- Mouse Anti-SCN5A Monoclonal Antibody (CBP708) (Cat#: NAB-0720-Z2720)
- Human Retinal Epithelial Cell ARPE-19 (Cat#: NCL2110P069)
- Human Astrocytes, Immortalized (Cat#: NCL-2105-P182-AM)
- Human Glial (Oligodendrocytic) Hybrid Cell Line (MO3.13) (Cat#: NCL-2108P34)
- Mouse Glioma Cell Line GL-261-Luc (Cat#: NCL-2108P06)
- Mouse Microglia N9 (Cat#: NCL2110P073)
- iNeu™ Human Neural Stem Cell Line (Cat#: NCL200552ZP)
- Rat Immortalized Retinal Muller Cell Line rMC-1 (Cat#: NCL-2106-S93)
- Mouse Glioma Cell Line GL261-GFP (Cat#: NCL-2108P04)
- Human Astrocytes (Cat#: NCC20-9PZ01)
- Rat Glioma Cell Line C6 (Cat#: NCL2110P346)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- AAV2 Full Capsids, Reference Standards (Cat#: NTC2101070CR)
- Dextran, NHS Activated (Cat#: NRZP-0722-ZP124)
- VSV-eGFP (Cat#: NTA-2011-ZP20)
- Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged (Cat#: NEP-0521-R0748)
- Lenti of Mouse synuclein, alpha (Snca) transcript variant (NM_001042451) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0864)
- Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0676)
- ABCA1 Antisense Oligonucleotide (NV-2106-P27) (Cat#: NV-2106-P27)
- Tau Antisense Oligonucleotide (IONIS-MAPTRx) (Cat#: NV-2106-P29)
- Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged (Cat#: NEP-0421-R0140)
- Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged (Cat#: NEP-0421-R0232)
- Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0497)
- Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged (Cat#: NEP-0621-R0041)
- Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0832)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP500)
- NeuroPro™ Anti-EPO BBB Shuttle Protein (Cat#: NRZP-0423-ZP508)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP498)
- NeuroPro™ Anti-NAGLU BBB Shuttle Protein (Cat#: NRZP-0423-ZP506)
- NeuroPro™ Anti-ASA BBB Shuttle Protein (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-PON1 BBB Shuttle Protein (Cat#: NRZP-0423-ZP507)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP502)
- NeuroPro™ Anti-Erythropoietin BBB Shuttle Protein (Cat#: NRZP-0423-ZP499)
- NeuroPro™ Anti-IDS BBB Shuttle Protein (Cat#: NRZP-0423-ZP503)