Product
iNeu™ Astrocytes
[CAT#: NCL-7P030]
Astrocytes differentiated from Human iPS cells, frozen
- Species:
- Human
- Cell Types:
- DopaNeuron
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Overview
Description
Astrocytes are specialized glial cells and are the most abundant cell type in the central nervous system (CNS). Astrocytes have traditionally been regarded as supporting cells of nervous tissue. Reactive astrocytes Cells are used as markers of damaged or diseased tissues. However, new research shows that astrocytes play an important and complex role in maintaining a healthy central nervous system and the occurrence and development of central nervous system diseases.
Creative Biolabs's iNeu® astrocytes are astrocytes derived from Human iPS cells. They provide an easily accessible, consistent and biologically relevant source of astrocytes for studying normal central nervous system function and synaptic transmission and plasticity in disease progression.
Creative Biolabs's iNeu® astrocytes are astrocytes derived from Human iPS cells. They provide an easily accessible, consistent and biologically relevant source of astrocytes for studying normal central nervous system function and synaptic transmission and plasticity in disease progression.
Features
>95% pure population of Human astrocytes
Expression of relevant astrocyte markers (e.g. S100β and GFAP)
Exhibition of cytokine-mediated inflammatory responses
Limited proliferative capacity and long-term viability
Ability to co-culture with Human neurons
Expression of relevant astrocyte markers (e.g. S100β and GFAP)
Exhibition of cytokine-mediated inflammatory responses
Limited proliferative capacity and long-term viability
Ability to co-culture with Human neurons
Cell Types
DopaNeuron
Application Notes
Normal CNS Functions
Synaptic remodeling and pruning
Neurotransmitter homeostasis
Neural network communication
Blood-brain barrier support
Regulation of CNS blood flow
CNS metabolism
Disease CNS Functions
Reactive astrogliosis and CNS inflammation
Neurodegenerative disease
Neuropsychiatric disease
Alexander disease and leukodystrophies
Multiple sclerosis and autoimmune inflammatory disorders
Infectious disease
Synaptic remodeling and pruning
Neurotransmitter homeostasis
Neural network communication
Blood-brain barrier support
Regulation of CNS blood flow
CNS metabolism
Disease CNS Functions
Reactive astrogliosis and CNS inflammation
Neurodegenerative disease
Neuropsychiatric disease
Alexander disease and leukodystrophies
Multiple sclerosis and autoimmune inflammatory disorders
Infectious disease
Species
Human
Properties
Size
1 Vial: ≥ 1 x 10^6 cells/vial
Tissue Source
Blood
Age
50-59
Mycoplasma Testing
The cell line has been screened using the Mycoplasma Detection Kit to confirm the absence of Mycoplasma contamination.
Shipping
Dry ice.
Storage
Liquid Nitrogen
Research Use Only
For research use only
Quality Control
All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Donor Information
Gender
Male
Donor Health
Parkinson's Disease
Ethnicity
Caucasian
Additional Donor Information
Genotype: NCA (A53T) c.209G>A
Publications
Publications (0)
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
