iNeuMab™ Anti-CD38 BBB Shuttle Antibody (NRZP-1022-ZP3883)

Name: iNeuMab™ Anti-CD38 BBB Shuttle Antibody (NRZP-1022-ZP3883)
SKU: NRZP-1022-ZP3883
Rating: 5 (1 reviews)

[CAT#: NRZP-1022-ZP3883]

Host Species:: Humanized

Species Reactivity:: Human

Applications:: ADCC; CDC; FC; In Vitro

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Humanized

Applications

ADCC; CDC; FC; In Vitro

Relevant Diseases

Parkinson's Disease; Multiple Sclerosis

Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only

Target

CD38

Official Name

CD38

Full Name

CD38 molecule

Alternative Names

Acute lymphoblastic leukemia cells antigen CD38;
ADP ribosyl cyclase 1;
ADP ribosyl cyclase;
ADP ribosyl cyclase/cyclic ADP-ribose hydrolase;
ADP-ribosyl cyclase 1;
ADPRC 1;
ADPRC1;
cADPr hydrolase 1;
CD 38;

Publications