iNeuMab™ Anti-IL-33 BBB Shuttle Antibody (NRZP-1022-ZP2914)

Name: iNeuMab™ Anti-IL-33 BBB Shuttle Antibody (NRZP-1022-ZP2914)
SKU: NRZP-1022-ZP2914
Rating: 5 (1 reviews)

[CAT#: NRZP-1022-ZP2914]

Host Species:: Mouse

Species Reactivity:: Human

Applications:: In Vitro; In Vivo; Neut

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Applications

In Vitro; In Vivo; Neut

Relevant Diseases

Alzheimer's Disease; Multiple Sclerosis

Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only

Target

IL-33

Official Name

IL33

Full Name

interleukin 33

Alternative Names

95-270; NF-HEV; Interleukin-33; C9orf26; IL1F11; 99-270; Interleukin-1 family member 11; IL-33; IL-1F11; Nuclear factor from high endothelial venules; NFEHEV; DVS27; 109-270

Publications