iNeuMab™ Anti-Malin BBB Shuttle Antibody (NRZP-0423-ZP257)
[CAT#: NRZP-0423-ZP257]
- Species Reactivity:
- Human
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-NHLRC1 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 2-125 (N-terminus encompassing RING domain) of human Malin (also known as NHL repeat-containing protein 1, E3 ubiquitin-protein ligase NHLRC1, NHLRC1 and EPM2B, accession number Q6VVB1)
Rat: 86% identity (97/112 amino acids identical)
Mouse: 77% identity (98/126 amino acids identical)
Rat: 86% identity (97/112 amino acids identical)
Mouse: 77% identity (98/126 amino acids identical)
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Research Areas
Rare Disease
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
NHLRC1
Official Name
NHLRC1
Full Name
Malin
Alternative Names
NHLRC1; EPM2A; EPM2B; MALIN; bA204B7.2; NHL repeat containing E3 ubiquitin protein ligase 1
Uniprot ID
Q6VVB1
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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