iNeuMab™ Anti-NPY2R BBB Shuttle Antibody (NRZP-0423-ZP309)
[CAT#: NRZP-0423-ZP309]
- Species Reactivity:
- Human; Rat; Mouse
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-NPY2R BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-51 (extracellular N-terminus) and 330-381 (cytoplasmic C-terminus) of human NPY2R (also known as Neuropeptide Y receptor type 2, Neuropeptide Y/peptide YYY2 receptor, NPY2-R, NPY-Y2 receptor, Y2 receptor and RCG62488, accession number P49146)
Mouse: 85% identity (44/52 amino acids identical) and 90% identity (47/52 amino acids identical)
Rat: 83% identity (43/52 amino acids identical) and 88% identity (46/52 amino acids identical)
Mouse: 85% identity (44/52 amino acids identical) and 90% identity (47/52 amino acids identical)
Rat: 83% identity (43/52 amino acids identical) and 88% identity (46/52 amino acids identical)
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Rat; Mouse
Clonality
Monoclonal
Isotype
IgG2a
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
NPY2R
Official Name
NPY2R
Full Name
NPY2R/Neuropeptide Y receptor type 2
Alternative Names
NPY2R; NPY2-R; Neuropeptide Y receptor Y2
Uniprot ID
P49146
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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