iNeuMab™ Anti-TSHR Antibody (NRP-0422-P1271)

Q: What type of control experiments should I conduct when using this antibody?

When using the antibody, it’s important to include appropriate positive and negative controls. Positive controls should include tissues or cells known to express TSHR. Negative controls might consist of tissues without TSHR expression or the use of an isotype control antibody. These controls help confirm the specificity and validity of your experimental results.

Q: What are the recommended secondary antibodies for use with Clone NR3128P?

For Clone NR3128P, use a secondary antibody that matches the primary host species (mouse) and is conjugated to a detection molecule such as HRP, alkaline phosphatase, or a fluorophore. Commonly recommended secondary antibodies include anti-mouse IgG conjugated to HRP, depending on your detection method. Always verify compatibility with your experimental setup.

Q: Is there customer support available if I encounter issues with the antibody, and what information should I provide?

Absolutely, our customer support team is here to assist you with any issues regarding the antibody. Please provide details such as the lot number, a brief description of the experiment, protocol used, and any troubleshooting steps already taken. This information will help us offer tailored advice and support to optimize your research outcomes.

Product Overview

Description

NRP-0422-P1271 is based on the induction of two thyroid stimulating mabs with full agonist TSHR activity.

Species Reactivity

Human; Mouse

Clonality

Monoclonal

Host Species

Mouse

Applications

In Vitro; In Vivo; Agonist

Relevant Diseases

Epilepsy; Peripheral Neuropathy

Product Properties

Preservatives

BSA Free

Concentration

1mg/mL

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only

Target

TSHR

Official Name

TSHR

Full Name

thyrotropin receptor

Alternative Names

TSHR; CHNG1; LGR3; hTSHR-I; thyroid stimulating hormone receptor; Thyrotropin receptor

Gene ID

7253(Human)

Uniprot ID

P16473(Human)

Publications

Publications (0)

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Scientific Resources

[Brochure]

Neuros Antibody Product Panel

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Customer Reviews and Q&As

Customer Reviews Average Customer Ratings Overall

5.0

Excellent

A vital addition to our studies

The antibody functions remarkably well as an agonist, stimulating TSHR signaling pathways with high specificity. The data we've gathered from these experiments have been consistent and reproducible, greatly enhancing the quality of our research.

Excellent

Outstanding results

Anti-TSHR antibody effectively mimics TSH activity, allowing us to explore TSHR-mediated pathways in detail. The specificity and potency of this antibody as an agonist are impressive, making it a valuable tool for our endocrine studies.

Excellent

The data have been robust and consistent

We've employed the antibody in various in vivo studies, and the outcomes have been consistently positive. It's a high-quality reagent that has significantly advanced our research on thyroid function.

Excellent

It has consistently exceeded our expectations

The antibody provides clear, specific staining in immunohistochemistry and robust bands in Western blot analyses. It's a reliable and effective reagent for thyroid receptor research.

Excellent

A valuable tool

The antibody's specificity in detecting TSH receptors has provided us with clear insights and reproducible results in various assays. It's a top-notch product for thyroid research.

Q&As

What type of control experiments should I conduct when using this antibody?

When using the antibody, it’s important to include appropriate positive and negative controls. Positive controls should include tissues or cells known to express TSHR. Negative controls might consist of tissues without TSHR expression or the use of an isotype control antibody. These controls help confirm the specificity and validity of your experimental results.

What are the recommended secondary antibodies for use with Clone NR3128P?

For Clone NR3128P, use a secondary antibody that matches the primary host species (mouse) and is conjugated to a detection molecule such as HRP, alkaline phosphatase, or a fluorophore. Commonly recommended secondary antibodies include anti-mouse IgG conjugated to HRP, depending on your detection method. Always verify compatibility with your experimental setup.

Is there customer support available if I encounter issues with the antibody, and what information should I provide?

Absolutely, our customer support team is here to assist you with any issues regarding the antibody. Please provide details such as the lot number, a brief description of the experiment, protocol used, and any troubleshooting steps already taken. This information will help us offer tailored advice and support to optimize your research outcomes.