iNeuMab™ Anti-VIP BBB Shuttle Antibody (NRZP-0423-ZP466)
[CAT#: NRZP-0423-ZP466]
- Species Reactivity:
- Human; Rat
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-VIP BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 81-152 (mature protein) of human VIP (also known as Vasoactive intestinal peptide and Vasoactive intestinal polypeptide, cleaved into Intestinal peptide PHI-42/PHV-42 for Peptide histidine valine 42 and Intestinal peptide PHM-27 for Peptide histidine methioninamide 27/Intestinal peptide PHI-27 for Peptide histidine isoleucinamide 27, accession number P01282)
Rat: 92% identity (66/72 amino acids identical)
Mouse: 90% identity (65/72 amino acids identical)
<50% identity with PACAP
Rat: 92% identity (66/72 amino acids identical)
Mouse: 90% identity (65/72 amino acids identical)
<50% identity with PACAP
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Rat
Clonality
Monoclonal
Isotype
IgG2b
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
VIP
Official Name
VIP
Full Name
VIP
Alternative Names
Vasoactive Intestinal Peptide; Prepro-VIP; VIP Peptides; PHM27;
Uniprot ID
P01282
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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