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Creative Biolabs
Product

IonON™ Human Kv1.4 Recombinant Stable Cell Line

[CAT#: NCL-7P089]

Creative Biolabs provides numerous IonON cell models of ion channels to meet your drug discovery needs.

Species:
Human
Applications:
Ion Channel Assay
Cell Types:
Ion Channel Cell

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Product Overview

Description

Main Kv1 subunits in mammalian brains are voltage-gated potassium channel subunits Kv1.1, Kv1.2, Kv1.3, Kv1.4, and Kv1.6. A crucial type A potassium channel that controls the excitability of neurons in the central nervous system is voltage-gated potassium channel Kv1.4. The behaviour of this channel is of particular clinical importance, as hypertrophy and heart failure can result from up-regulation of Kv1.4 expression.

Cell Types

Ion Channel Cell

Applications

Ion Channel Assay

Application Notes

Electrophysiology assay (Conventional and automated patch clamp platforms)

Species

Human
Properties

Size

2 Vials of mycoplasma-free cells, 1 mL per vial aliquots containing 2M to 4M cells/mL in DMSO

Mycoplasma Testing

The cell line has been screened using the Mycoplasma Detection Kit to confirm the absence of Mycoplasma contamination.

Shipping

Dry ice.

Storage

Liquid Nitrogen

Research Use Only

For research use only

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Target Details

Target

Kv1.4

Official Name

KCNA4

Alternative Names

K2p4.1; KCNK4; TRAAK; TRAAK1; Two pore K(+) channel KT4.1
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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