iPSC Derived Neural Progenitors (Human)
Derived from induced pluripotent stem (iPS) cells
- Cell Assay
- Cell Types:
- Neural Stem Cell; Neural Progenitor Cell; iPSC
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
These hiPSC-derived NPCs proliferate into adherent cell monolayers, and the expression of appropriate neural stem cell markers including Nestin and Sox-2 exceeds 80%. The cells are provided at the 3rd generation and can be expanded 3 to 5 times using Estem ™ Neural Expansion Medium (NCC200529ZP). By using Human ES / iPS Neuronal Differentiation Medium (NCC200538ZP) or Estem ™ Neuronal Differentiation Medium (NCC200541ZP), human NPC can be further differentiated into terminal neurons. Differentiation results in more than 80-90% of cells mainly expressing neuronal markers bIII-tubulin and MAP2.
Human iPSC-derived NPCs can be used in a variety of research applications, including neurotoxicity studies, co-culture applications, and screening molecules that induce or inhibit preferential differentiation into mature neurons.
Growing cells: Growing cell cultures should be checked on receipt using an inverted microscope. Immediately check the cell density upon arrival for any obvious defects. If the cell density is too high (more than 80% confluent) subculture the cells (harvest and reseed) immediately.
For detailed instructions on the thawing procedure of frozen cells and the culture of adherent or suspended cells, please feel free to contact us by email or phone.