Mouse Anti-CHRNA7 Monoclonal Antibody (CBP2645)

[CAT#: NAB20101719CR]

Mouse Monoclonal (2H1G3) to CHRNA7

Host Species:: Mouse

Species Reactivity:: Human

Applications:: IHC; WB; ELISA

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Product Overview

Description

Nicotinic acetylcholine receptors (nAChRs) are cholinergic receptors that form ligand-gated ion channels that mediate fast signal transmission at synapses. CHRNA7 (neuronal acetylcholine receptor subunit alpha-7) forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin.

Expression Host

Mammalian cells

Immunogen

CHRNA7 fusion protein Ag15980

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b

Clone Number

CBP2645

Applications

IHC; WB; ELISA

Application Notes

IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Neural Cell

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1200 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

CHRNA7

Official Name

CHRNA7

Full Name

Cholinergic receptor, nicotinic, alpha 7

Alternative Names

CHRNA7; CHRNA7 2; NACHRA7

Gene ID

1139(Human); 11441(Mouse)

Uniprot ID

P36544(Human); P49582(Mouse)

References

1. Tillman, T. S., Alvarez, F. J., Reinert, N. J., Liu, C., Wang, D., Xu, Y.,... & Tang, P. (2016). Functional Human α7 Nicotinic Acetylcholine Receptor (nAChR) Generated from Escherichia coli. Journal of Biological Chemistry, 291(35), 18276-18282.

Publications