Creative Biolabs

Mouse Anti-MKI67 Monoclonal Antibody (AB161)

[CAT#: NAB2007FY1716]

Progenitors

Host Species:
Mouse
Species Reactivity:
Human
Applications:
IHC; IF

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Description
The antigen KI-67, also known as Ki-67 or MKI67, is a protein encoded by the MKI67 gene in humans (an antigen recognized by the monoclonal antibody Ki-67). Antigen KI-67 is a nuclear protein associated with cell proliferation. Changing the expression level of Ki-67 does not significantly affect cell proliferation in vivo. Ki-67 mutant mice develop normally, and cells lacking Ki-67 proliferate effectively. In addition, it is related to ribosomal RNA transcription. Inactivation of KI-67 antigen leads to inhibition of ribosomal RNA synthesis.
Epitope
Binds to an located within the peptide sequence PLSLSTCLFGRGIEC
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
AB161
Applications
IHC; IF
Application Notes
IHC: 1:200-1:500
IF: 2-10 µg/ml
Form
Liquid
Formulation
PBS, pH 7.2, 40% glycerol
Preservatives
0.02% Sodium azide
Concentration
1 mg/ml
Purification
Protein A purified
Shipping
Gel Pack
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Handling Advice
The antibody solution should be gently mixed before use.
Research Use Only
For research use only
Target
Ki67
Official Name
MKI67
Full Name
Antigen KI-67
Alternative Names
MKI67; marker of proliferation Ki-67; KIA; MIB-; MIB-1; PPP1R105
Gene ID
4288(Human); 17345(Mouse); 246042(Rat)
Uniprot ID
P46013(Human); E9PVX6(Mouse)
For Research Use Only. Not For Clinical Use.
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