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Creative Biolabs
Product

Mouse Anti-PFN1 Monoclonal Antibody (CBP6810)

[CAT#: NAB2007FY1759]

Amyotrophic Lateral Sclerosis,
Parkinson's, Alzheimer's and Huntington's diseases

Host Species:
Mouse
Species Reactivity:
Human
Applications:
IHC; WB

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Product Overview

Description

Neurodegenerative diseases, such as amyotrophic lateral sclerosis, Parkinson's disease, Alzheimer's disease and Huntington's disease The result of the gradual loss of neuron structure and function, Causes neuron death. Profilin-1 is a protein encoded by the PFN1 gene in humans. The protein encoded by this gene is a ubiquitous actin monomer binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. The deletion of this gene is related to Miller-Dieker syndrome. Mutations in this gene may be a rare cause of amyotrophic lateral sclerosis (also known as Lou Gehrig's disease).

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a

Clone Number

CBP6810

Applications

IHC; WB

Application Notes

IHC: 1:1000-1:2500
WB: 1 µg/ml

Relevant Diseases

Alzheimer's Disease; Huntington's Disease; Parkinson's Disease; Amyotrophic Lateral Sclerosis
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, 40% glycerol

Preservatives

0.02% Sodium azide

Concentration

0.5 mg/ml

Purification

Protein A purified

Shipping

Gel Pack

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling Advice

The antibody solution should be gently mixed before use.

Research Use Only

For research use only
Target

Target

Profilin 1

Official Name

PFN1

Full Name

Profilin 1

Alternative Names

PFN1; ALS18; Profilin 1

Gene ID

5216(Human); 18643(Mouse); 64303(Rat)

Uniprot ID

P07737(Human); P62962(Mouse); P62963(Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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