Creative Biolabs

Mouse Beta-Synuclein Antibody

[CAT#: NAB-2102-MP93]

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat; Bovine; Porcine
Applications:
ICC; WB; IF

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Description
β-synuclein is a member of the synuclein protein family. The other two members are α and γ-synuclein. Each protein is encoded by a different but related gene. α-synuclein was originally isolated as a major synaptic vesicle-related protein from the electrical organs of fish. Direct homologs of α-synuclein have been found in all vertebrates. Later studies linked the expression of α-synuclein to several human brain pathologies, making it the main component of Lewy bodies in Parkinson's disease. β-synuclein, as a protein that is obviously related to α-synuclein but different from α-synuclein, was isolated as a component of the brain of normal people and patients. The human β-synuclein molecule has a size of 134 amino acids, while the α-synuclein molecule has a size of 140 amino acids, and the n-terminal part of the two molecules is actually the same, while the c-terminal region is more variable.
Immunogen
C-terminal peptide of human ?-synuclein EPEGESYEDPPQEEYQEYEPEA coupled to KLH
Species Reactivity
Human; Mouse; Rat; Bovine; Porcine
Host Species
Mouse
Isotype
IgG
Applications
ICC; WB; IF
Application Notes
Immunofluorescent: 1:1,000 Immunocytochemistry: 1:1,000 Western Blot: 1:1,000
Form
liquid
Purification
Affinity Purified
Shipping
Frozen (Polar Packs)
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Target
Beta Synuclein
Official Name
SNCB
Full Name
beta Synuclein
Alternative Names
SNCB; entrez:6620; synuclein beta
Gene ID
6620 (Human); 104069 (Mouse); 113893 (Rat)
Uniprot ID
Q16143 (Human); Q91ZZ3 (Mouse); Q 63754 (Rat)
For Research Use Only. Not For Clinical Use.
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