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Creative Biolabs
Product

Mouse O9-1 Cranial Neural Crest Cell Line

[CAT#: NCL-2108-P015]

The O9-1 cell line stably expresses stem cell markers (CD44, Sca-1, and Bmi1) and neural crest markers (AP-2a, Twist1, Sox9, Myc, Ets1, Dlx1, Dlx2, Crabp1, Epha2, and Itgb1).

Species:
Mouse
Applications:
Cell Culture
Cell Types:
Neural Crest Cell

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Product Overview

Description

Cranial neural crest cells also give rise to melanocytes, corneal endothelial cells, peripheral nervous system neurons, and glial cells in addition to ectomesenchymal derivatives including cranial bones, cartilage, smooth muscle, and dentin. Although multipotent stem-like cells may exist during the development of the cranial neural crest, prior research has revealed that they are ephemeral and undergo lineage restriction early in embryonic development.

Cell Types

Neural Crest Cell

Applications

Cell Culture

Application Notes

The O9-1 cell line should serve as a useful tool for investigating the molecular properties of differentiating cranial neural crest cells. The O9-1 cell line can be propagated and passaged for at least 10 passages, and can differentiate into osteoblasts, chondrocytes, smooth muscle cells, and glial cells.

Species

Mouse
Properties

Size

>1x10^6 Cells

Research Use Only

For research use only

Quality Control

• Each vial contains ≥ 1X10^6 viable cells at passage 20 -22
• Cells tested negative for infectious disease by a murine PCR panel (Mouse Essential CLEAR Panel by Charles River Animal Diagnostic Services)
• Cells tested negative for mycoplasma contamination
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For Research Use Only. Not For Clinical Use.
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