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![](static/images/product/product-icon-neural-antibodies.png)
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- DB; ELISA; FC; IHC; In Vitro
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryDescription
Species Reactivity
Clonality
Host Species
Clone Number
Applications
Relevant Diseases
Formulation
Preservatives
Concentration
Purification
Purity
Endotoxin Level
Low Endotoxin < 1 EU/mg
Shipping
Storage
Research Use Only
Figure 1 shows the results of inhibition ELISA using this antibody.
Rats were treated with intraocular injections of 3H4 Fab solution (2.4 pg/eye) compared to sham or vehicle controls. Statistical significance is shown.
![](https://img.creative-biolabs.com/neuros/productImages/NRP-0523-P534-1.png)
Figure 2 shows the Pepscan results of a dot blot epitope assay for the monoclonal antibodies Syn-F1, Syn-F2, Syn-O1, Syn-O2, Syn-O3 and Syn-O4, and the Syn-1 antibody as a control.
Rats were treated with intraocular injections of 3H4 Fab solution (2.4 pg/eye) compared to sham or vehicle controls. Statistical significance is shown.
![](https://img.creative-biolabs.com/neuros/productImages/NRP-0523-P534-2.png)
Figure 3 shows the results of a sandwich ELISA for the detection of phosphorylated Ser129-α-synuclein aggregates.
Rats were treated with intraocular injections of 3H4 Fab solution (2.4 pg/eye) compared to sham or vehicle controls. Statistical significance is shown.
![](https://img.creative-biolabs.com/neuros/productImages/NRP-0523-P534-3.png)
Figure 4 shows the immunohistochemical analysis of Parkinson's disease tissue.
Rats were treated with intraocular injections of 3H4 Fab solution (2.4 pg/eye) compared to sham or vehicle controls. Statistical significance is shown.
![](https://img.creative-biolabs.com/neuros/productImages/NRP-0523-P534-4.png)
Figure 5 shows the percentage of dot-positive cells for each antibody tested.
Rats were treated with intraocular injections of 3H4 Fab solution (2.4 pg/eye) compared to sham or vehicle controls. Statistical significance is shown.
![](https://img.creative-biolabs.com/neuros/productImages/NRP-0523-P534-5.png)
Publications (0)
ExcellentAs a postdoc working on synaptic proteins, I found the antibody to be highly reliableIt provides clear and distinct bands in Western blotting and excellent staining in immunofluorescence. The antibody has significantly improved our ability to detect alpha-synuclein in various samples.
ExcellentGave us confidence in our findingsWe use the antibody for detecting alpha-synuclein in both human and mouse samples. The cross-reactivity is minimal, and the results are consistent and reliable. This has been a valuable tool in our study of neurodegenerative disorders.
ExcellentHighly recommended for any neuroscience labIn our quest to understand the pathology of Parkinson's disease, the antibody has been indispensable. The antibody's performance in immunofluorescence microscopy is particularly noteworthy, providing clear and detailed images of alpha-synuclein localization.
ExcellentIt's a top-tier product for alpha-synuclein detectionWe've been using the antibody for over a year now, and it's never disappointed. The antibody provides strong, clear bands in our Western blots and beautiful staining in our immunohistochemistry studies.
ExcellentA reliable reagentWe've been using the antibody for our studies on alpha-synuclein aggregation. The results have been consistently excellent, with clear detection of oligomers and fibrils in our assays. This antibody is a must-have for anyone researching synucleinopathies.