NeuroMab™ Anti-Amyloid Beta BBB Shuttle Antibody(NRZP-1022-ZP4063)
[CAT#: NRZP-1022-ZP4063]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- In Vitro
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Applications
In Vitro
Relevant Diseases
Alzheimer's Disease
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
AmyloidBeta
Official Name
Amyloid Beta
Full Name
Amyloid Beta
Alternative Names
APP; Aβ; Abeta; Amyloid β
Product Pictures
IHC
Figure 1 Immunostaining of mouse APP/PS1 sections with ni3A and pa2H.
FuncS
Figure 2 In vivo imaging of Aβ after direct application to the brain.
FuncS
Figure 3 Blood clearance of VHH-pa2H-DTPA-111 In in APP swe /PS1dE9 transgenic mice (APP/PS1) and wild-type (WT) littermates.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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