NeuroMab™ Anti-Cavβ1 calcium channel BBB Shuttle Antibody, Clone N7/18
[CAT#: NRZP-0423-ZP66]
- Species Reactivity:
- Human; Rat; Mouse
- Applications:
- WB; IHC; IP; ICC
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-CACNB1 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Synthetic peptide amino acids 19-34 (PMEVFDPSPQGKYSKR) of human Cav1 (also known as Voltage-dependent L-type calcium channel subunit beta-1, Calcium channel voltagedependent subunit beta 1, Cacnb1, Cacnlb1 and CAB1, accession number Q02641)
Rat: 100% identity (16/16 amino acids identical)
Mouse: 100% identity (16/16 amino acids identical)
100% identity between all Cav1 splice variants
<50% identity with Cav2, Cav3 and Cav4
Rat: 100% identity (16/16 amino acids identical)
Mouse: 100% identity (16/16 amino acids identical)
100% identity between all Cav1 splice variants
<50% identity with Cav2, Cav3 and Cav4
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Rat; Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
N7/18
Applications
WB; IHC; IP; ICC
Application Notes
Does not cross-react with Cavβ2, Cavβ3 or Cavβ4
Research Areas
Ca2+ channels
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
CACNB1
Official Name
CACNB1
Full Name
Cavbeta1 Ca2+ channel
Alternative Names
CACNB1; Calcium channel; voltage-dependent; beta 1 subunit
Uniprot ID
Q02641
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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