Product
NeuroMab™ Anti-Cavβ2 calcium channel subunit BBB Shuttle Antibody, Clone N8b/1
[CAT#: NRZP-0423-ZP67]
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; IHC; IP; ICC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-CACNB2 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Synthetic peptide amino acids 189-205 of rat Cavβ2 (RSPKPSANSVTSPHSKE; accession number NP_446303)
Human: 100% identity
Mouse=100% identity
Common to all Cavβ2 splice variants
Human: 100% identity
Mouse=100% identity
Common to all Cavβ2 splice variants
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
N8B/1
Applications
WB; IHC; IP; ICC
Application Notes
Does not crossreact with Cavβ1, Cavβ3, Cavβ4
Research Areas
Ca2+ channels
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
CACNB2
Official Name
CACNB2
Full Name
Cavbeta2 Ca2+ channel
Alternative Names
CACNB2; CACNLB2; CAVB2; MYSB; calcium voltage-gated channel auxiliary subunit beta 2; CAB2
Uniprot ID
NP_446303
Product Pictures
IB
Fig. 1 Adult rat brain membrane immunoblot.
IHC
Fig. 2 Adult rat pontine nucleus immunohistochemistry
IHC
Fig. 3 Adult rat hippocampus immunohistochemistry
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
