NeuroMab™ Anti-Cav3.1 Ca2+ channel BBB Shuttle Antibody, Clone N178A/9
[CAT#: NRZP-0423-ZP64]
- Species Reactivity:
- Rat; Mouse; Human
- Applications:
- WB; IHC; ICC
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-CACNA1G BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1 (also known as Voltage-gated/dependent T-type calcium channel alpha-1-G subunit, Cacna1g and NBR13, accession number Q9WUT2)
Rat: 96% identity (117/121 amino acids identical)
Human: 80% identity (98/122 amino acids identical)
<30% identity with Cav3.2
Rat: 96% identity (117/121 amino acids identical)
Human: 80% identity (98/122 amino acids identical)
<30% identity with Cav3.2
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse; Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
N178A/9
Applications
WB; IHC; ICC
Research Areas
Ca2+ channels
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
CACNA1G
Official Name
CACNA1G
Full Name
Cav3.1 Ca2+ channel
Alternative Names
CACNA1G; Calcium channel; voltage-dependent; T type; alpha 1G subunit
Uniprot ID
Q9WUT2
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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