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Creative Biolabs

NeuroMab™ Anti-CGRP BBB Shuttle Antibody(NRZP-1222-ZP982)

[CAT#: NRZP-1222-ZP982]

Host Species:
Mouse
Species Reactivity:
Human
Applications:
Antagonist; In Vitro

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. Creative Biolabs has developed a BBB shuttle antibody platform that actively transports these large biomolecules across the BBB via receptor-mediated transcytosis (RMT). The engineered BBB shuttle antibody is believed to significantly increase the uptake of therapeutic molecules in the brain.

Species Reactivity

Human

Host Species

Mouse

Applications

Antagonist; In Vitro

Relevant Diseases

Multiple Sclerosis; Migraine
Target

Target

CGRP

Official Name

CGRP

Full Name

Calcitonin gene-related peptide

Alternative Names

CALC1; CALCA
Publications

Publications (0)

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