NeuroMab™ Anti-IL-6 Antibody, Clone cCLB8
Functional antibody against Human IL-6
- Host Species:
- Chimeric
- Species Reactivity:
- Human
- Applications:
- WB; Inhib; Neut; In Vitro; In Vivo
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryDescription
Species Reactivity
Clonality
Host Species
Clone Number
Applications
Formulation
Preservatives
Concentration
Purification
Purity
Endotoxin Level
Low Endotoxin < 1 EU/mg
Shipping
Storage
Research Use Only
Figure 1 shows a graph showing the binding of cCLB8 to human recombinant IL-6.
Figure 2 graph showing the inhibition of IL-6-mediated IgM mu secretion from SKW6.4 cells by cCLB8.
Figure 3 is a graph showing the inhibition of IL-6-mediated MCP-1 production by cCLB8.
Figure 4. Western blot images showing cCLB8 inhibits IL-6 signaling in THP-1 human monocytic leukemia cells.
Figure 5 is a graph showing that cCLB8 inhibits IL-6-induced serum amyloid A production in HepG2 cells.
Figure 6 is a graph showing the ability of cCLB8 to neutralize rhIL-6-induced cell proliferation.
Figure 7 is a graph showing the relative reduction in body weight loss in tumor-bearing mouse hosts treated with anti-human and anti-mouse IL-6 antibodies.
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