NeuroMab™ Anti-IL-6 Antibody (NRP-0422-P1501)
Functional antibody against Human IL-6
- Host Species:
- Mouse; Humanized; Chimeric
- Species Reactivity:
- Human
- Applications:
- Antagonist; In Vivo; In Vitro; Block; Inhib
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Lot Number
SPECIFIC INQUIRY
inquiryDescription
Immunogen
Species Reactivity
Clonality
Host Species
Applications
Formulation
Preservatives
Concentration
Purification
Purity
Endotoxin Level
Low Endotoxin < 1 EU/mg
Shipping
Storage
Research Use Only
Figure 1 shows the results of experiments reflecting the binding of exemplary antibodies to Fc-IL6Ralpha-IL6.
Figure 2 shows the results of experiments reflecting the binding of exemplary antibodies to IL-6.
Figure 3 shows the results of experiments reflecting the binding of exemplary antibodies of the invention to non-covalently complexed IL-6 and IL-6Rα.
Figure 4 shows the results of experiments illustrating the ability of exemplary antibodies to block haptoglobin release from HepG2 cells stimulated with Fc-IL6Ralpha-IL6 complexes.
Figure 6 shows the results of experiments reflecting the binding of exemplary antibodies to IL-6Ralpha alone.
Figure 7 illustrates the pharmacokinetic properties of exemplary antibodies.
Figure 8 shows the results of experiments reflecting the in vivo inhibition of haptoglobin secretion by exemplary antibodies.
Figure 9 shows the experimental results reflecting inhibition of lung metastasis.
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