NeuroMab™ Anti-Nav1.6 sodium channel BBB Shuttle Antibody, Clone K87A/10
[CAT#: NRZP-0423-ZP282]
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; IHC; IP; ICC
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-SCN8A BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Synthetic peptide 459-476 (intracellular interdomain loop I-II) of rat Nav1.6 (accession number NP_062139)
Human: 88% identity (16/18 amino acids identical)
Mouse=100% identity (18/18 amino acids identical)
Human: 88% identity (16/18 amino acids identical)
Mouse=100% identity (18/18 amino acids identical)
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
K87A/10
Applications
WB; IHC; IP; ICC
Research Areas
Na+ channels
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
SCN8A
Official Name
SCN8A
Full Name
Nav1.6 Na+ channel
Alternative Names
SCN8A; CERIII; CIAT; EIEE13; MED; NaCh6; Nav1.6; PN4; sodium voltage-gated channel alpha subunit 8; BFIS5; MYOCL2
Uniprot ID
NP_062139
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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